Conference report: Third annual young researcher forum of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine
Conference report: Third annual young researcher forum of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine
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会议报告：日本传统医学医学与药学学会第三届年度青年研究员论坛
DOI：
10.1002/tkm2.1362
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Nakashima Souichi
中科院分区：
文献类型：
--
作者：
Yoshino Tetsuhiro;Yokogawa Takami;Nakamichi Kohsuke;Manse Yoshiaki;Yoshikawa Hayato;Sasaki Hiroaki;Ando Hirokazu;Nakashima Souichi
四名年轻研究人员在第三届年度青年研究人员论坛上介绍了他们在日本传统草药（Wakan-yaku）领域的研究，该论坛名为“尊重和打破禁忌”，在日本传统医学医学和制药科学学会2022年年会前一周举行。Yokogawa博士介绍了她的研究重点是阿育吠陀药物洗脱线Kshara Sutra治疗肛瘘的机制，报告了其对肛瘘大鼠模型肛门组织的影响及其对大肠杆菌和金黄色葡萄球菌（肛瘘的致病微生物）的抗菌活性。Nakamichi先生介绍了他的研究，重点是汉方药物的抗肥胖效果与肠道微生物群组成之间的关系。他的研究结果部分揭示了bofutsushosan和boiogito影响小鼠的脂质代谢，并与肠道微生物群组成相关。Manse博士报告了Enmei-so（Isodonis Herba）中二萜类成分的抗炎活性，揭示了其对活化巨噬细胞释放的一氧化氮和炎症细胞因子的新型抑制活性，并确定了有助于抑制和作用机制的活性成分。Yoshikawa先生报告了从药用植物Valeriana fauriei和Hypericum erectum中分离出的小分子化合物的抗癌活性。他的研究结果表明，五种化合物可能通过抑制HSP 105表达来增加人宫颈癌细胞对阿霉素的敏感性。这次活动是在网上进行的，有78人参加。我们打算在2023年和未来举办并改进这一论坛。
Four young researchers presented their studies in the field of traditional Japanese herbal medicine (Wakan‐yaku) at the third annual young researcher forum entitled “Respecting and Breaking Traditions,” held 1 week before the 2022 annual meeting of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine. Dr. Yokogawa presented her research focusing on the mechanism of the Ayurveda drug‐eluting string, Kshara Sutra, in treating anal fistulas, reporting on its effects on the anal tissue in an anal fistula rat model and its antibacterial activity againstEscherichia coliandStaphylococcus aureus, the causative organisms of anal fistulas. Mr. Nakamichi presented his research focusing on the relationship between the efficacy of Kampo medicines with anti‐obesity effects and intestinal microbiota composition. His results partially revealed that bofutsushosan and boiogito affect lipid metabolism in mice and correlate with the intestinal microbiota composition. Dr. Manse reported the anti‐inflammatory activity of diterpenoid components in Enmei‐so (Isodonis Herba), revealing its novel inhibitory activity on nitric oxide released from activated macrophages and on inflammatory cytokines, and identified active components contributing to the inhibition and the mechanism of action. Mr. Yoshikawa reported the anticancer activity of small molecular compounds isolated from the medicinal plants,Valeriana faurieiandHypericum erectum. His results suggest that five compounds may increase the sensitivity of human cervical carcinoma cells to adriamycin via HSP105 expression suppression. The event was conducted online, and included 78 participants. We intend to hold and improve this forum in 2023 and the future.
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会议报告：日本传统医学医学与药学学会第二届年度青年研究员论坛
DOI：
10.1002/tkm2.1311
发表时间：
2022
期刊：
Traditional & Kampo Medicine
影响因子：
--
作者：
Yoshino Tetsuhiro;Yoneda Taichi;Yang Ximeng;Nishihara Masakazu;Ogawa Keiko;Kitamura Masashi;Ando Hirokazu;Nakashima Souichi;Horie Ichiro
通讯作者：
Horie Ichiro
使用特定抑制剂靶向细胞生存因子、HSF1 和 HSP 进行癌症治疗
DOI：
10.3191/thermalmed.33.1
发表时间：
2017
期刊：
Thermal Medicine
影响因子：
--
作者：
K. Ohtsuka
通讯作者：
K. Ohtsuka
阿育吠陀医学Kshara的研究（2）.1）日本替代Kshara Sutra的制备
DOI：
--
发表时间：
2005
期刊：
--
影响因子：
--
作者：
Michiyo Yoshimitsu;M. Mikage;Y. Nakagawa;Katsuya Yamamoto;K. Tazawa
通讯作者：
K. Tazawa
改进金泽经、肛瘘药线的药理评价
影响因子：
3.3
作者：
T. Yokogawa;Yohei Sasaki;Hirokazu Ando;Katsuya Yamamoto;M. Mikage
通讯作者：
M. Mikage