The venoarteriolar response of the skin in healthy legs measured at different depths.
The venoarteriolar response of the skin in healthy legs measured at different depths.
复制标题
在不同深度测量健康腿部皮肤的静脉小动脉反应。
DOI：
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
P. Kolari
中科院分区：
文献类型：
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作者：
K. Malanin;P. Kolari
本文对20例健康人下肢皮肤的静脉-动脉反应（VAR）进行了研究。在实验性静脉高压为30 mmHg、45 mmHg和60 mmHg时，将平卧位大腿周围充气袖带产生的激光多普勒流量（LDF）与坐位LDF进行比较。同时在皮肤表面毛细血管层（543 nm）和更深毛细血管层（780 nm）的相同部位测量皮肤的LDF。在543 nm处，LDF在任何袖带压力下与坐姿记录的LDF没有显著差异，而在780 nm处，LDF在30 mmHg袖带压力下显著高于坐姿LDF（P = 0.002）。543 nm处的VAR比780 nm处的VAR弱得多，并且VAR值的分散性很高。坐位时543 nm处的VAR为9.3%，780 nm处的VAR为34.6%（P < 0.001）。袖带压力为30 mmHg时，543 nm处的VAR与坐位引起的VAR无显著差异，而袖带压力为30 mmHg时，780 nm处的VAR显著小于坐位引起的VAR（P = 0.001）。尽管VAR值的高度分散，这些结果表明，在浅表毛细血管层的VAR是较小的，它达到最大值在较低的静脉高压，比VAR在较深的毛细血管层。
The venoarteriolar response (VAR) of the skin in healthy legs of 20 subjects was investigated. The laser Doppler flux (LDF), at an experimental venous hypertension of 30 mmHg, 45 mmHg and 60 mmHg, produced by a pneumatic cuff around the thigh in a recumbent position, was compared with the LDF in a sitting position. The LDF of the skin was measured simultaneously at the same site of the superficial capillary layer (with 543 nm) and of the deeper capillary layer (with 780 nm). At 543 nm the LDF did not differ significantly at any cuff pressure from the LDF recorded in a sitting position, whereas at 780 nm the LDF was significantly higher at the cuff pressure of 30 mmHg than the LDF in a sitting position (P = 0.002). The VAR was much weaker at 543 nm than at 780 nm, and the scatter of the VAR values was high. In a sitting position the VAR at 543 nm was 9.3% and at 780 nm 34.6% (P < 0.001). The VAR at 543 nm at the cuff pressure of 30 mmHg did not differ significantly from the VAR caused by the sitting position, whereas at 780 nm the VAR at the cuff pressure of 30 mmHg was significantly less than the VAR caused by the sitting position (P = 0.001). Despite the high scatter of the VAR values, these findings suggest that the VAR in the superficial capillary layer is smaller, and that it reached maximum at lower venous hypertension, than the VAR in the deeper capillary layer.
影响因子：
6.5
作者：
ANDERSON, RR;PARRISH, JA
通讯作者：
PARRISH, JA