The dynamic structure of arterioles.
The dynamic structure of arterioles.
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DOI：
10.1111/j.1742-7843.2011.00813.x
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发表时间：
2012-01
影响因子：
3.1
通讯作者：
Martinez-Lemus LA
中科院分区：
文献类型：
--
作者：
Martinez-Lemus LA
小动脉是血管树的动脉侧中的血管，其位于毛细血管的近端，并且与终末动脉一起提供对血流的大部分阻力。因此，小动脉是调节平均动脉压和组织灌注的重要因素。它们的壁由细胞和细胞外成分组成，传统上被分为三层：内膜，含有位于基底膜上的内皮细胞;由1层或2层平滑肌并列的内弹性膜制成的介质;以及主要由胶原束、神经末梢和一些成纤维细胞组成的外膜。小动脉壁的这些组分动态地相互连接，为小动脉壁提供一定程度的可塑性，这模糊了刚性分层分类的传统边界。本文综述了小动脉壁的结构形态，并展示了壁成分如何在空间、功能和时间上相互作用以控制血管直径、调节血流和维持血管通透性。
Arterioles are the blood vessels in the arterial side of the vascular tree that are located proximal to the capillaries and, in conjunction with the terminal arteries, provide the majority of resistance to blood flow. Consequently, arterioles are important contributors to the regulation of mean arterial pressure and tissue perfusion. Their wall consists of cellular and extracellular components that have been traditionally classified as conforming three layers: an intima containing endothelial cells sited on a basement membrane; a media made of an internal elastic lamina apposed by 1 or 2 layers of smooth muscle; and an adventitia composed mostly of collagen bundles, nerve endings and some fibroblasts. These components of the arteriolar wall are dynamically interconnected providing a level of plasticity to the arteriolar wall that blurs the traditional boundaries of a rigid layered classification. This review focuses on the structural conformation of the arteriolar wall and shows how wall components interact spatially, functionally, and temporally to control vascular diameter, regulate blood flow, and maintain vascular permeability.
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影响因子：
5.6
作者：
GIRARD, PR;NEREM, RM
通讯作者：
NEREM, RM
影响因子：
5.3
作者：
Imamura, Hirotoshi;Ohta, Tsuyoshi;Kikuta, Ken-ichiro
通讯作者：
Kikuta, Ken-ichiro
影响因子：
2.9
作者：
Belkin, AM;Zemskov, EA;Strongin, AY
通讯作者：
Strongin, AY
影响因子：
8.3
作者：
Heerkens, EHJ;Shaw, L;Heagerty, AM
通讯作者：
Heagerty, AM
DOI：
10.1016/s0022-5320(83)90083-7
发表时间：
1983-01-01
期刊：
JOURNAL OF ULTRASTRUCTURE RESEARCH
影响因子：
--
作者：
GABELLA, G
通讯作者：
GABELLA, G