The probability of sudden unexpected death in epilepsy given postictal prone position.
The probability of sudden unexpected death in epilepsy given postictal prone position.
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癫痫患者在俯卧位下猝死的概率。
DOI：
10.1016/j.yebeh.2021.107775
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发表时间：
2021-03
影响因子：
2.6
通讯作者：
Lee, Jong Woo
中科院分区：
文献类型：
--
作者：
Esmaeili, Behnaz;Dworetzky, Barbara A.;Glynn, Robert J.;Lee, Jong Woo
癫痫意外猝死（SUDEP）与全身性强直阵挛发作（GTCS）后立即发生的俯卧位密切相关。GTCS后发生SUDEP的风险尚未估计。我们使用贝叶斯分析计算了GTCS后给定俯卧位的SUDEP概率，该分析的输入来自已知的SUDEP风险和GTCS后俯卧位的概率。俯卧位SUDEP的风险估计为0.41%（95%可信区间0.13-0.69%）。GTCS后俯卧位与非俯卧位SUDEP的相对风险估计为63（95%可信区间30-96）。癫痫的意外猝死可以通过在癫痫发作后重新定位患者以避免俯卧位来预防。
Sudden Unexpected Death in Epilepsy (SUDEP) is strongly linked to prone position in the immediate aftermath of a generalized tonic-clonic seizure (GTCS). The risk of SUDEP after a GTCS resulting in prone position has not yet been estimated. We calculated the probability of SUDEP given prone position after a GTCS using Bayesian analysis with inputs obtained from known risk of SUDEP and probability of prone position after a GTCS. The risk for SUDEP given the prone position is estimated to be 0.41% (95% Credible Interval 0.13–0.69%). The relative risk of SUDEP in prone vs. non-prone position following a GTCS is estimated to be 63 (95% Credible Interval 30–96). Sudden Unexpected Death in Epilepsy might be prevented by repositioning the patient after a seizure to avoid the prone position.
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