Menstrually related mood disorders and a history of abuse: moderators of pain sensitivity.
Menstrually related mood disorders and a history of abuse: moderators of pain sensitivity.
复制标题
月经相关的情绪障碍和虐待史:疼痛敏感性的调节因素。
DOI:
10.1037/a0031900
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
Girdler,SusanS
中科院分区:
文献类型:
--
作者:
Fleischman,DianaS;Bunevicius,Adomas;Leserman,Jane;Girdler,SusanS
ObjectiveWomen with a menstrually related mood disorder (MRMD) have substantially higher rates of physical and sexual abuse and are more sensitive to experimental pain stimuli than women without a MRMD. For the first time, this study examined pain sensitivity and hormonal correlates in women with a MRMD and in non-MRMD controls as a function of abuse history.MethodsA total of 126 women (63 with MRMD, 34 with an abuse history; and 63 non-MRMD, 31 with an abuse history) were evaluated for:(1) sensitivity to cold pressor and forearm ischemic pain and (2) basal plasma cortisol and norepinephrine (NE) concentrations. Exploratory analyses examined relationships between plasma cortisol and NE concentrations and pain sensitivity.ResultsWomen with a MRMD and an abuse history showed increased sensitivity to both cold pressor and ischemic pain and lower basal cortisol concentrations, an effect not seen in the women without a MRMD. In all women, the expected relationship between greater plasma cortisol concentration and reduced sensitivity to pain was observed, whereas NE predicted pain sensitivity only in women with a MRMD.ConclusionsMenstrually related mood disorder status moderates the effect of a history of abuse on pain sensitivity. The results also suggest that the hypocortisolemia documented in the women with a MRMD and an abuse history may contribute to their greater sensitivity to noxious pain stimuli. This study adds to a growing body of evidence suggesting that a history of abuse may identify a clinically distinct subgroup of women with a MRMD.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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DOI:
10.1176/ajp.141.5.684
发表时间:
1984
期刊:
The American journal of psychiatry
影响因子:
--
作者:
David R. Rubinow;Peter Roy;M. Hoban;Philip W. Gold;Robert M. Post
通讯作者:
Robert M. Post
影响因子:
7.4
作者:
W. Hall
通讯作者:
W. Hall
DOI:
10.1111/j.1471-0528.2001.00120.x
发表时间:
2001
期刊:
BJOG: An International Journal of Obstetrics & Gynaecology
影响因子:
--
作者:
M. Steiner;S. Romano;S. Babcock;Julia Dillon;Cathy Shuler;C. Berger;D. Carter;R. Reid;D. Stewart;S. Steinberg;R. Judge
通讯作者:
R. Judge
影响因子:
7.4
作者:
GRACELY, RH;MCGRATH, P;DUBNER, R
通讯作者:
DUBNER, R
影响因子:
2.9
作者:
Granot, Michal;Somer, Eli;Yovell, Yoram
通讯作者:
Yovell, Yoram