Menstrually related mood disorders and a history of abuse: moderators of pain sensitivity.

Menstrually related mood disorders and a history of abuse: moderators of pain sensitivity.
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月经相关的情绪障碍和虐待史:疼痛敏感性的调节因素。

DOI:
10.1037/a0031900
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发表时间:
2014
期刊:
Health psychology : official journal of the Division of Health Psychology, American Psychological Association
影响因子:
--
通讯作者:
Girdler,SusanS
Girdler,SusanS
中科院分区:
--
文献类型:
--
作者:
Fleischman,DianaS;Bunevicius,Adomas;Leserman,Jane;Girdler,SusanS

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患有精神相关情绪障碍(MRMD)的女性比没有MRMD的女性有更高的身体和性虐待率,对实验性疼痛刺激更敏感。第一次,本研究探讨了疼痛的敏感性和激素相关的妇女与MRMD和非MRMD控制作为滥用history.MethodsA的功能,共126名妇女(63 MRMD,34与滥用历史;和63非MRMD,31与滥用历史)进行了评价:(1)敏感性冷加压和前臂缺血性疼痛和(2)基础血浆皮质醇和去甲肾上腺素(NE)浓度。探索性分析研究血浆皮质醇和NE浓度和pain sensitivity.ResultsWomen与MRMD和滥用史之间的关系表现出增加的敏感性,冷加压和缺血性疼痛和较低的基础皮质醇浓度,没有看到在妇女没有MRMD的效果。在所有妇女中,更大的血浆皮质醇浓度和降低对疼痛的敏感性之间的预期关系进行了观察,而NE预测疼痛敏感性只有在妇女与MRMD.ConclusionsMenstrually相关的情绪障碍状态缓和的影响,滥用对疼痛敏感性的历史。结果还表明,低皮质醇血症记录在妇女与MRMD和滥用历史可能有助于他们更敏感的伤害性疼痛刺激。这项研究增加了越来越多的证据表明,虐待史可能会确定一个临床上不同的亚组妇女与MRMD。(PsycINFO数据库记录(c)2016阿帕,保留所有权利)
ObjectiveWomen with a menstrually related mood disorder (MRMD) have substantially higher rates of physical and sexual abuse and are more sensitive to experimental pain stimuli than women without a MRMD. For the first time, this study examined pain sensitivity and hormonal correlates in women with a MRMD and in non-MRMD controls as a function of abuse history.MethodsA total of 126 women (63 with MRMD, 34 with an abuse history; and 63 non-MRMD, 31 with an abuse history) were evaluated for:(1) sensitivity to cold pressor and forearm ischemic pain and (2) basal plasma cortisol and norepinephrine (NE) concentrations. Exploratory analyses examined relationships between plasma cortisol and NE concentrations and pain sensitivity.ResultsWomen with a MRMD and an abuse history showed increased sensitivity to both cold pressor and ischemic pain and lower basal cortisol concentrations, an effect not seen in the women without a MRMD. In all women, the expected relationship between greater plasma cortisol concentration and reduced sensitivity to pain was observed, whereas NE predicted pain sensitivity only in women with a MRMD.ConclusionsMenstrually related mood disorder status moderates the effect of a history of abuse on pain sensitivity. The results also suggest that the hypocortisolemia documented in the women with a MRMD and an abuse history may contribute to their greater sensitivity to noxious pain stimuli. This study adds to a growing body of evidence suggesting that a history of abuse may identify a clinically distinct subgroup of women with a MRMD.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
月经相关情绪障碍的前瞻性评估。
DOI: 10.1176/ajp.141.5.684
发表时间: 1984
期刊: The American journal of psychiatry
影响因子: --
作者:
David R. Rubinow;Peter Roy;M. Hoban;Philip W. Gold;Robert M. Post
通讯作者: Robert M. Post
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DOI: --
发表时间: 1981
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影响因子: 7.4
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W. Hall
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DOI: 10.1111/j.1471-0528.2001.00120.x
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影响因子: --
作者:
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DOI: 10.1016/0304-3959(78)90020-9
发表时间: 1978-01-01
期刊: PAIN
影响因子: 7.4
作者:
GRACELY, RH;MCGRATH, P;DUBNER, R
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DOI: 10.1097/ajp.0b013e3182132963
发表时间: 2011-09-01
影响因子: 2.9
作者:
Granot, Michal;Somer, Eli;Yovell, Yoram
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