Nonphotic phase shifting in the old and the cold.

Nonphotic phase shifting in the old and the cold.
复制标题

旧时和寒冷时的非光相变。

DOI:
--
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发表时间:
1994
影响因子:
2.8
通讯作者:
S. Biello
S. Biello
中科院分区:
医学4区
文献类型:
--
作者:
Nicholas Mrosovsky;S. Biello

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When confined to novel running wheels or when given injections of triazolam in their home cages, old hamsters do not become as active as young hamsters. Therefore, lack of nonphotic phase shifting following such manipulations may stem from insufficient activity or arousal. Phase advances can be obtained in some 10-month-old animals when wheel running during the pulse is increased by the presence of females in estrous condition and in most 18-month-old hamsters by combining confinement to a novel wheel with triazolam injections. These data suggest that there is relatively little if anything wrong in aging hamsters with the nonphotic phase-shifting mechanism itself. The reason why in certain situations old hamsters do not shift appears to be because the nonphotic inputs to these shifting mechanisms are not strong enough. However, when running in novel wheels is increased by carrying out the tests at cold temperatures, most old animals did not show subsequent phase shifts. Evidently it is not running per se that is critical for phase shifts, but probably the motivational context for such running.
衰老会改变活动-休息周期对生物钟的反馈影响。
DOI: 10.1152/ajpregu.1992.263.4.r981
发表时间: 1992
期刊: The American journal of physiology
影响因子: --
作者:
VanReeth,O;Zhang,Y;Zee,PC;Turek,FW
通讯作者: Turek,FW
DOI: 10.1093/sleep/15.4.322
发表时间: 1992-08-01
期刊: SLEEP
影响因子: 5.6
作者:
MONK, TH;REYNOLDS, CF;KUPFER, DJ
通讯作者: KUPFER, DJ
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DOI: 10.1016/0024-3205(87)90564-9
发表时间: 1987
期刊: Life sciences
影响因子: 6.1
作者:
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通讯作者: Losee-Olson,SH