Long-term costs of introducing HPV-DNA post-treatment surveillance to national cervical cancer screening in Ireland.
Long-term costs of introducing HPV-DNA post-treatment surveillance to national cervical cancer screening in Ireland.
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DOI：
10.1586/14737167.2015.1057126
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发表时间：
2015
影响因子：
2.3
通讯作者：
Basu A
中科院分区：
文献类型：
--
作者：
Agapova M;Duignan A;Smith A;O'Neill C;Basu A
作为爱尔兰宫颈癌监测的一部分，联合检测（细胞学加人乳头瘤病毒 DNA 检测）增加了一次性检测成本。政策制定者感兴趣的是这些成本的长期影响，以及对未检测到异常的女性的召回强度的下降。使用决策分析模型对纯细胞学检测和联合检测进行了成本分析，汇总了 12 年来两种策略的检测利用率和成本。联合检测策略的累计增量成本在前 3 年为正值，但此后变为负值，在 12 年期间，仅细胞学策略节省了约 2000 万欧元的成本。通过一系列关于折扣和流失率的敏感性分析，结果是稳健的。该分析为政策制定者提供了宝贵的信息，有助于在爱尔兰引入治疗后监测联合检测。
Co-testing (cytology plus human papillomavirus DNA testing) as part of cervical cancer surveillance in Ireland increases one-time testing costs. Of interest to policy makers was the long-term impact of these costs accompanied by decreases in intensity of recalls for women with no detected abnormalities. A cost-analysis of cytology-only and co-testing was implemented using decision analytic modeling, aggregating testing utilization and costs for each of the two strategies over 12 years. Aggregated incremental costs of the co-testing strategy were positive for the first 3 years but became negative thereafter, generating a cost savings of roughly €20 million in favor of the cytology-only strategy over a 12-year period. Results were robust over a range of sensitivity analyses with respect to discount and attrition rates. This analysis provided valuable information to policy makers contributing to the introduction of co-testing for post-treatment surveillance in Ireland.
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影响因子：
6.4
作者：
Bulk, S;Visser, O;Meijer, CJLM
通讯作者：
Meijer, CJLM
影响因子：
4.5
作者：
Sullivan, Sean D.;Mauskopf, Josephine A.;Shau, Wen-Yi
通讯作者：
Shau, Wen-Yi
DOI：
10.1136/bmj.e7086
发表时间：
2012-10-31
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Legood R;Smith M;Lew JB;Walker R;Moss S;Kitchener H;Patnick J;Canfell K
通讯作者：
Canfell K
影响因子：
105.7
作者：
Rebolj, Matejka;Helmerhorst, Theo;van Ballegooijen, Marjolein
通讯作者：
van Ballegooijen, Marjolein
影响因子：
1.3
作者：
Jordan, J.;Martin-Hirsch, P.;Prendiville, W.
通讯作者：
Prendiville, W.