Love-related changes in the brain: a resting-state functional magnetic resonance imaging study.
Love-related changes in the brain: a resting-state functional magnetic resonance imaging study.
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大脑中与爱情相关的变化：静息态功能磁共振成像研究
DOI：
10.3389/fnhum.2015.00071
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发表时间：
2015
影响因子：
2.9
通讯作者：
Zhang X
中科院分区：
文献类型：
--
作者：
Song H;Zou Z;Kou J;Liu Y;Yang L;Zilverstand A;d'Oleire Uquillas F;Zhang X
浪漫爱情是一种动机状态，与进入或保持与特定其他人的密切关系的愿望有关。功能性磁共振成像（fMRI）研究发现，当浪漫的恋人看到他们伴侣的照片时，大脑中涉及奖励，动机和情绪调节的区域的激活增加。然而，关于浪漫的爱情是否会影响大脑在休息时的功能结构，我们知之甚少。在本研究中，收集了静息状态功能磁共振成像（rsfMRI）数据，以比较区域同质性（ReHo）和功能连接性（FC）在“恋爱”组中的差异（LG，N = 34，目前正处于热恋中），一个“失恋”组（ELG，N = 34，最近结束了恋爱关系），和一个“单身”组（SG，N = 32，从未恋爱）。结果表明：（1）左侧背侧前扣带皮层（dACC）ReHo显著增加（2）左前扣带回ReHo与恋爱时间呈正相关，与失恋时间呈负相关;（3）奖励、动机和情绪调节网络中的FC（dACC，杏仁核，尾状核，杏仁核和丘脑核）以及社会认知网络中的FC [颞顶连接（TPJ），后扣带皮层（PCC），内侧前额叶皮层（MPFC）、下顶叶、楔前叶和颞叶]在LG中显著增加（与ELG和SG相比）;（4）在两个网络的大部分区域中，LG中FC与恋爱持续时间呈正相关，而ELG中FC与失恋持续时间呈负相关。这项研究提供了第一个与爱情有关的大脑功能结构改变的经验证据。此外，这些结果揭示了浪漫爱情的潜在神经机制，并证明了应用静息态fMRI方法研究浪漫爱情的可能性。
Romantic love is a motivational state associated with a desire to enter or maintain a close relationship with a specific other person. Functional magnetic resonance imaging (fMRI) studies have found activation increases in brain regions involved in the processing of reward, motivation and emotion regulation, when romantic lovers view photographs of their partners. However, not much is known about whether romantic love affects the brain’s functional architecture during rest. In the present study, resting state functional magnetic resonance imaging (rsfMRI) data was collected to compare the regional homogeneity (ReHo) and functional connectivity (FC) across an “in-love” group (LG, N = 34, currently intensely in love), an “ended-love” group (ELG, N = 34, ended romantic relationship recently), and a “single” group (SG, N = 32, never fallen in love). Results show that: (1) ReHo of the left dorsal anterior cingulate cortex (dACC) was significantly increased in the LG (in comparison to the ELG and the SG); (2) ReHo of the left dACC was positively correlated with length of time in love in the LG, and negatively correlated with the lovelorn duration since breakup in the ELG; (3) FC within the reward, motivation, and emotion regulation network (dACC, insula, caudate, amygdala, and nucleus accumbens) as well as FC in the social cognition network [temporo-parietal junction (TPJ), posterior cingulate cortex (PCC), medial prefrontal cortex (MPFC), inferior parietal, precuneus, and temporal lobe] was significantly increased in the LG (in comparison to the ELG and SG); (4) in most regions within both networks FC was positively correlated with the duration of love in the LG but negatively correlated with the lovelorn duration of time since breakup in the ELG. This study provides first empirical evidence of love-related alterations in brain functional architecture. Furthermore, the results shed light on the underlying neural mechanisms of romantic love, and demonstrate the possibility of applying a resting-state fMRI approach for investigating romantic love.
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影响因子：
4.1
作者：
Aouizerate, B;Cuny, E;Burbaud, P
通讯作者：
Burbaud, P
影响因子：
7.6
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CLARK, MS;MILLS, J
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MILLS, J
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2.5
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AERTSEN, AMHJ;GERSTEIN, GL;PALM, G
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影响因子：
4.2
作者：
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影响因子：
1.7
作者：
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通讯作者：
Zeki, S