Acute kidney injury in elderly persons.

Acute kidney injury in elderly persons.
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DOI:
10.1053/j.ajkd.2009.12.034
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发表时间:
2010-07
期刊:
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子:
--
通讯作者:
Coca SG
Coca SG
中科院分区:
其他
文献类型:
--
作者:
Coca SG

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急性肾损伤(AKI)的发病率在老年患者中最高,他们在整个人口中所占的比例越来越大。这些患者的AKI与短期和长期死亡以及包括终末期肾脏疾病在内的慢性肾脏疾病的风险增加有关。与年轻人相比,老年患者的AKI是否具有更大的相对风险目前尚不清楚。其他领域,如与健康相关的生活质量,可能会在AKI发作后受到轻微影响。目前还没有有效的治疗AKI的方法可供广泛使用。然而,由于AKI在老年人中的发病率最高,而且在所有人群中,AKI的表型与AKI没有明显差异,因此未来应在老年人群中进行AKI干预的随机对照试验。
The incidence rate of acute kidney injury (AKI) is highest in elderly patients, who comprise an ever-growing segment of the population at large. AKI in these patients is associated with an increased risk of short-term and long-term death and chronic kidney disease, including end-stage renal disease. Whether AKI in older individuals carries a larger relative risk for these outcomes compared to younger individuals in unclear at this time. Other domains such as health-related quality of life may be mildly impacted after an episode of AKI. No effective therapies for AKI are currently available for wide-spread use. However, since the incidence of AKI is highest in the elderly and the phenotype is not discernibly different from AKI in all populations, future randomized controlled trials of interventions for AKI should be performed in the elderly population.
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