IL-6 Cooperates with G-CSF To Induce Protumor Function of Neutrophils in Bone Marrow by Enhancing STAT3 Activation

IL-6 Cooperates with G-CSF To Induce Protumor Function of Neutrophils in Bone Marrow by Enhancing STAT3 Activation
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IL-6与G-CSF协同增强STAT3激活诱导骨髓中性粒细胞促肿瘤功能

DOI:
10.4049/jimmunol.1201881
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发表时间:
2013-06
影响因子:
4.4
通讯作者:
Feng, Zuo-Hua
Feng, Zuo-Hua
中科院分区:
医学2区
文献类型:
--
作者:
Shu, Yu;Wang, Qi;Zhang, Gui-Mei;Feng, Zuo-Hua

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已知中性粒细胞具有抗肿瘤潜力。然而,近年来中性粒细胞的促肿瘤作用已得到很好的证明。到目前为止,尚不清楚是什么原因导致中性粒细胞的功能从肿瘤抑制性转化为肿瘤抑制性。
Neutrophils are known to have antitumor potential. However, in recent years the tumor-promoting effect of neutrophils has been well demonstrated. So far, it remains unclear what causes the conversion of neutrophil function from tumor suppressive to tumor
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