Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
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DOI：
10.18632/aging.104016
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发表时间：
2020-11-07
期刊：
影响因子：
--
通讯作者：
Kim KW
中科院分区：
文献类型：
--
作者：
Suh SW;Han JW;Han JH;Bae JB;Moon W;Kim HS;Oh DJ;Kwak KP;Kim BJ;Kim SG;Kim JL;Kim TH;Ryu SH;Moon SW;Park JH;Byun S;Seo J;Youn JC;Lee DY;Lee DW;Lee SB;Lee JJ;Jhoo JH;Kim KW
主观年龄相关睡眠变化 (AACS) 和 AACS 中的性别差异从未在老年人群中进行过前瞻性研究。我们在总共 6 年中每两年对参加韩国认知老化和痴呆症纵向研究的 4,686 名 60 岁或以上社区居住健康男性和女性进行 AACS 比较。在基线和每次随访时使用匹兹堡睡眠质量指数测量睡眠参数，包括睡眠持续时间、潜伏期和效率、睡眠中期时间、白天功能障碍和总体主观睡眠质量。使用线性混合效应模型分析时间和性别对主观睡眠参数的影响。在 6 年的随访中，我们观察到总体而言，睡眠潜伏期增加，而日间功能障碍和睡眠质量恶化。研究发现，AACS 存在显着的性别差异，女性在 6 年内表现出睡眠持续时间缩短、睡眠中期时间延迟以及睡眠效率下降。两组的睡眠质量均恶化，但女性的变化更为明显。临床医生在确定何时治疗该人群已声明的睡眠障碍时应谨慎。
Subjective age-associated changes in sleep (AACS) and sex differences in AACS have never been prospectively investigated in elderly populations. We compared the AACS every 2 years over a total of 6 years between 4,686 community-dwelling healthy men and women aged 60 years or older who participated in the Korean Longitudinal Study on Cognitive Aging and Dementia. Sleep parameters including sleep duration, latency, and efficiency, mid-sleep time, daytime dysfunction, and overall subjective sleep quality were measured using the Pittsburgh Sleep Quality Index at baseline and at each follow-up. The effects of time and sex on subjective sleep parameters were analyzed using linear mixed-effects models. During the 6 years of follow-up, we observed that overall, sleep latency increased, while daytime dysfunction and sleep quality worsened. Significant sex differences in AACS was found, with women showing shortened sleep duration, delayed mid-sleep time, and decreased sleep efficiency over 6 years. Sleep quality worsened in both groups but a more pronounced change was observed in women. Clinicians should be cautious in determining when to treat declared sleep disturbances in this population.
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