Preventing obesity during infancy: a pilot study.
Preventing obesity during infancy: a pilot study.
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DOI：
10.1038/oby.2010.182
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发表时间：
2011-02
期刊：
影响因子：
6.9
通讯作者：
Birch, Leann L.
中科院分区：
文献类型：
--
作者：
Paul, Ian M.;Savage, Jennifer S.;Anzman, Stephanie L.;Beiler, Jessica S.;Marini, Michele E.;Stokes, Jennifer L.;Birch, Leann L.
超过 20% 的 2 至 5 岁美国儿童体重超重，这表明预防肥胖的努力必须更早开始。这项研究测试了向父母提供的两种行为干预措施的独立和综合效果，旨在促进婴儿第一年的健康成长。从产科病房招募了打算母乳喂养的母亲和新生儿二人组。采用 2 × 2 设计，160 名双人组被随机分配到四个治疗室之一，在两次护士家访中接受两种干预措施、一种干预措施或不接受干预措施。第一个干预措施（“安抚/睡眠”）指导父母区分饥饿和婴儿痛苦的其他来源。我们教导安抚策略，以尽量减少因非饥饿相关的烦躁而进食，并延长睡眠时间，尤其是在晚上。第二项干预措施（“引入固体食物”）向父母传授饥饿和饱腹感的线索、引入固体食物的时机，以及如何通过反复接触来克服婴儿最初对健康食品的排斥。共有 110 名母婴夫妇完成了这项为期一年的研究。 1 岁时，接受两种干预措施的婴儿的体重身长百分位数较低 (P = 0.009)。接受这两种干预措施的参与者的平均身长体重处于第 33 个百分位；相比之下，其他研究组中的参与者仅在首次干预时就达到了较高的水平——第 50 个百分位；仅第二次干预——第 56 个百分位；对照组——第 50 个百分位）。这表明多成分行为干预可能具有长期预防肥胖的潜力（ClinicalTrials.gov 编号，NCT00359242）。
More than 20% of US children between ages 2 and 5 years are overweight suggesting efforts to prevent obesity must begin earlier. This study tested the independent and combined effects of two behavioral interventions delivered to parents, designed to promote healthy infant growth in the first year. Mother–newborn dyads intending to breastfeed were recruited from a maternity ward. With a 2 × 2 design, 160 dyads were randomized into one of four treatment cells to receive both, one, or no interventions delivered at two nurse home visits. The first intervention (“Soothe/Sleep”) instructed parents on discriminating between hunger and other sources of infant distress. Soothing strategies were taught to minimize feeding for non-hunger-related fussiness and to prolong sleep duration, particularly at night. The second intervention (“Introduction of Solids”) taught parents about hunger and satiety cues, the timing for the introduction of solid foods, and how to overcome infants’ initial rejection of healthy foods through repeated exposure. A total of 110 mother–infant dyads completed the year-long study. At 1 year, infants who received both interventions had lower weight-for-length percentiles (P = 0.009). Participants receiving both interventions had a mean weight-for-length in the 33rd percentile; in contrast, those in other study groups were higher first intervention only—50th percentile; second intervention only—56th percentile; control group—50th percentile).This suggests that multicomponent behavioral interventions may have potential for long-term obesity prevention (ClinicalTrials.gov number, NCT00359242).
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影响因子：
105.7
作者：
EID, EE
通讯作者：
EID, EE
影响因子：
158.5
作者：
Barker, DJP;Osmond, C;Eriksson, JG
通讯作者：
Eriksson, JG
影响因子：
5.2
作者：
EATONEVANS, J;DUGDALE, AE
通讯作者：
DUGDALE, AE
影响因子：
7.1
作者：
Jouret, Beatrice;Ahluwalia, Namanjeet;Tauber, Maithe
通讯作者：
Tauber, Maithe
影响因子：
5.2
作者：
Griffiths, L. J.;Smeeth, L.;Dezateux, C.
通讯作者：
Dezateux, C.