ReadySim: A computational framework for building explicit finite element musculoskeletal simulations directly from motion laboratory data.
ReadySim: A computational framework for building explicit finite element musculoskeletal simulations directly from motion laboratory data.
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DOI：
10.1002/cnm.3396
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发表时间：
2020-11
影响因子：
2.1
通讯作者：
Shelburne KB
中科院分区：
文献类型：
--
作者：
Hume DR;Rullkoetter PJ;Shelburne KB
肌肉骨骼建模使研究人员能够深入了解关节力学，这可能无法通过体内或体外研究获得。常见的肌肉骨骼建模技术涉及刚体动力学软件，通常采用简化的关节表示。这些表示已被证明是有用的，但在进行单框架变形分析的结构感兴趣的限制。肌肉骨骼有限元（MSFE）分析允许足够详细地表示结构，以获得内部应力和应变的精确解，包括复杂的接触条件和材料表示。直接在有限元框架中进行肌肉力量优化的研究通常在复杂性上受到限制，以最大限度地减少计算时间。最近在计算效率和肌肉力量预测控制方案方面的进展使这些解决方案更加实用。然而，制定特定主题的模拟仍然是一个具有挑战性的问题。这项工作的目标是开发一个开源的计算框架，以建立和运行模拟（a）规模的MSFE模型的大小和有效地估计（B）关节运动学和（c）肌肉力量从人体运动数据收集在一个典型的步态实验室。使用MATLAB和Python构建计算框架，以与模型输入和输出文件进行接口。该软件使用实验室标记数据来缩放模型节段长度并估计关节运动学。基于估计的运动学和地面反作用力执行并发肌肉力和组织应变估计。该软件将提高单框架MSFE模拟的可用性和一致性。软件和模板模型都可以在SimTK上免费获得。直接在有限元环境中进行单框架肌肉骨骼建模，用于肌肉力估计和组织应变分析。开放发布单侧肌肉骨骼有限元模型及软件使用稿件
Musculoskeletal modeling allows researchers insight into joint mechanics which might not otherwise be obtainable through in vivo or in vitro studies. Common musculoskeletal modeling techniques involve rigid body dynamics software which often employ simplified joint representations. These representations have proven useful but are limited in performing single-framework deformable analyzes in structures of interest. Musculoskeletal finite element (MSFE) analysis allows for representation of structures in sufficient detail to obtain accurate solutions of the internal stresses and strains including complex contact conditions and material representations. Studies which performed muscle force optimization directly in a finite element framework were often limited in complexity to minimize computational time. Recent advances in computational efficiency and control schemes for muscle force prediction have made these solutions more practical. Yet, the formulation of subject-specific simulations remains a challenging problem. The objectives of this work were to develop an open-source computational framework to build and run simulations which (a) scale the size of MSFE models and efficiently estimate (b) joint kinematics and (c) muscle forces from human motion data collected in a typical gait laboratory. A computational framework was built using MATLAB and Python to interface with model input and output files. The software uses laboratory marker data to scale model segment lengths and estimate joint kinematics. Concurrent muscle force and tissue strain estimations are performed based on the estimated kinematics and ground reaction forces. This software will improve the usability and consistency of single-framework MSFE simulations. Both software and template model are made freely available on SimTK. Single framework musculoskeletal modeling directly in a finite element environment for muscle force estimation and tissue strain analysis. Open dissemination of unilateral musculoskeletal finite element model and software used in manuscript
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影响因子：
3.8
作者：
Lenhart RL;Kaiser J;Smith CR;Thelen DG
通讯作者：
Thelen DG
DOI：
10.1115/1.4002854
发表时间：
2010-12-01
影响因子：
1.7
作者：
Fitzpatrick, Clare K.;Baldwin, Mark A.;Rullkoetter, Paul J.
通讯作者：
Rullkoetter, Paul J.
影响因子：
2.4
作者：
FORWOOD, MR;NEAL, RJ;WILSON, BD
通讯作者：
WILSON, BD
DOI：
10.1115/1.4023523
发表时间：
2013-04-01
影响因子：
1.7
作者：
Fiorentino, Niccolo M.;Lin, Jonathan S.;Blemker, Silvia S.
通讯作者：
Blemker, Silvia S.
影响因子：
2.4
作者：
Halloran, Jason P.;Ackermann, Marko;Erdemir, Ahmet;van den Bogert, Antonie J.
通讯作者：
van den Bogert, Antonie J.