The role of organic osmolytes in osmoregulation: from bacteria to mammals.
The role of organic osmolytes in osmoregulation: from bacteria to mammals.
复制标题
有机渗透剂在渗透调节中的作用:从细菌到哺乳动物。
DOI:
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复制
发表时间:
1993
期刊:
影响因子:
--
通讯作者:
R. Kinne
中科院分区:
文献类型:
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作者:
R. Kinne
Cells of marine species are known to establish osmotic balance with their environment by adjusting the concentrations of organic osmolytes rather than inorganic osmolytes such as sodium, potassium, and chloride. These organic osmolytes fall into three classes: polyhydric alcohols such as sorbitol, amino acids and amino acid derivatives, and urea and trimethylamines. Substantial evidence is available for a central role of each of these classes in osmoregulation in marine species. In this chapter information on the importance of organic osmolytes is extended to a study of isolated mammalian kidney cells. The intracellular concentration of organic osmolytes in these cells responds dramatically to changes in the osmotic environment. The release of sorbitol following hypoosmotic exposure appears to be triggered by calcium, possibly via a mechanism involving membrane recycling. The summarized experiments provide a basis for further work in marine species.
DOI:
10.1152/ajpcell.1988.255.5.c581
发表时间:
1988
期刊:
The American journal of physiology
影响因子:
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作者:
Arend,LJ;Burnatowska-Hledin,MA;Spielman,WS
通讯作者:
Spielman,WS
影响因子:
2.9
作者:
Billadello,JJ;Gard,JK;Ackerman,JJ;Gross,RW
通讯作者:
Gross,RW
影响因子:
6.6
作者:
Brown,D;Weyer,P;Orci,L
通讯作者:
Orci,L