The role of organic osmolytes in osmoregulation: from bacteria to mammals.

The role of organic osmolytes in osmoregulation: from bacteria to mammals.
复制标题

有机渗透剂在渗透调节中的作用:从细菌到哺乳动物。

DOI:
--
复制
发表时间:
1993
期刊:
The Journal of experimental zoology
影响因子:
--
通讯作者:
R. Kinne
R. Kinne
中科院分区:
--
文献类型:
--
作者:
R. Kinne

文献摘要

参考文献

被引文献

相似文献

众所周知,海洋物种的细胞通过调节有机渗透物的浓度而不是无机渗透物(如钠、钾和氯化物)的浓度来建立与环境的渗透平衡。这些有机渗透物分为三类:多羟基醇,如山梨醇、氨基酸和氨基酸衍生物、尿素和三甲胺。有大量证据表明,这些类别中的每一类在海洋物种的渗透调节中都起着核心作用。在本章中,关于有机渗透剂的重要性的信息扩展到分离的哺乳动物肾细胞的研究。这些细胞中有机渗透物的细胞内浓度对渗透环境的变化有显著的反应。低渗暴露后山梨醇的释放似乎是由钙触发的,可能是通过一种涉及膜再循环的机制。总结的实验结果为进一步开展海洋物种研究奠定了基础。
Cells of marine species are known to establish osmotic balance with their environment by adjusting the concentrations of organic osmolytes rather than inorganic osmolytes such as sodium, potassium, and chloride. These organic osmolytes fall into three classes: polyhydric alcohols such as sorbitol, amino acids and amino acid derivatives, and urea and trimethylamines. Substantial evidence is available for a central role of each of these classes in osmoregulation in marine species. In this chapter information on the importance of organic osmolytes is extended to a study of isolated mammalian kidney cells. The intracellular concentration of organic osmolytes in these cells responds dramatically to changes in the osmotic environment. The release of sorbitol following hypoosmotic exposure appears to be triggered by calcium, possibly via a mechanism involving membrane recycling. The summarized experiments provide a basis for further work in marine species.
皮质集合管细胞中腺苷受体介导的钙动员。
DOI: 10.1152/ajpcell.1988.255.5.c581
发表时间: 1988
期刊: The American journal of physiology
影响因子: --
作者:
Arend,LJ;Burnatowska-Hledin,MA;Spielman,WS
通讯作者: Spielman,WS
DOI: 10.1016/0003-2697(85)90116-2
发表时间: 1985
影响因子: 2.9
作者:
Billadello,JJ;Gard,JK;Ackerman,JJ;Gross,RW
通讯作者: Gross,RW
加压素刺激肾集合管主细胞的内吞作用。
DOI: --
发表时间: 1988
影响因子: 6.6
作者:
Brown,D;Weyer,P;Orci,L
通讯作者: Orci,L