Common neural mechanisms supporting spatial working memory, attention and motor intention.
Common neural mechanisms supporting spatial working memory, attention and motor intention.
复制标题
DOI：
10.1016/j.neuropsychologia.2010.12.020
复制
发表时间：
2011-05
期刊：
影响因子：
2.6
通讯作者：
Curtis CE
中科院分区：
文献类型：
--
作者：
Ikkai A;Curtis CE
前额叶皮层（PFC）和后顶叶皮层（PPC）是工作记忆的关键神经基质。在维持工作记忆表征期间，这些区域的神经活动持续存在。因此，持久活动可能是暂时维持信息的神经机制。然而，表示的本质或这种持久活动实际表示的内容尚不清楚。在这篇综述中，我们总结了我们实验室最近进行的功能磁共振成像（fMRI）研究，这些研究测试了有关各种空间认知任务期间持续活动性质的假设。我们发现，PFC 和 PPC 中在维持工作记忆表征期间表现出持续活动的相同区域，在维持空间注意力和维持运动意图期间也表现出持续活动。因此，我们得出的结论是，持续活动并不特定于工作记忆，而是携带可普遍用于支持各种认知的信息。具体来说，可以读出 PFC 和 PPC 中优先空间的地形组织地图中的活动，以指导注意力分配、空间记忆和运动规划。
The prefrontal cortex (PFC) and posterior parietal cortex (PPC) are critical neural substrates for working memory. Neural activity persists in these regions during the maintenance of a working memory representation. Persistent activity, therefore, may be the neural mechanism by which information is temporarily maintained. However, the nature of the representation or what is actually being represented by this persistent activity is not well understood. In this review, we summarize the recent functional magnetic resonance imaging (fMRI) studies conducted in our laboratory that test hypotheses about the nature of persistent activity during a variety of spatial cognition tasks. We find that the same areas in the PFC and PPC that show persistent activity during the maintenance of a working memory representation also show persistent activity during the maintenance of spatial attention and the maintenance of motor intention. Therefore, we conclude that persistent activity is not specific to working memory, but instead, carries information that can be used generally to support a variety of cognitions. Specifically, activity in topographically organized maps of prioritized space in PFC and PPC could be read out to guide attention allocation, spatial memory, and motor planning.
登录
查看更多内容
影响因子：
56.9
作者：
FUSTER, JM;ALEXANDER, GE
通讯作者：
ALEXANDER, GE
影响因子：
3.2
作者：
Corbetta, M;Kincade, JM;Shulman, GL
通讯作者：
Shulman, GL
DOI：
10.1093/cercor/bhp002
发表时间：
2009-10
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Anton-Erxleben K;Stephan VM;Treue S
通讯作者：
Treue S
DOI：
10.1523/jneurosci.4465-09.2009
发表时间：
2009-12-16
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Armstrong KM;Chang MH;Moore T
通讯作者：
Moore T
影响因子：
25
作者：
Chawla, D;Rees, G;Friston, KJ
通讯作者：
Friston, KJ