Motor cortex activity predicts response alternation during sensorimotor decisions.
Motor cortex activity predicts response alternation during sensorimotor decisions.
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DOI：
10.1038/ncomms13098
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发表时间：
2016-10-07
影响因子：
16.6
通讯作者：
Siegel, Markus
中科院分区：
文献类型：
--
作者：
Pape, Anna-Antonia;Siegel, Markus
我们的行动始终受到基于感官信息的决策的指导。运动皮层传统上被视为此过程中的最终输出阶段，仅根据这些决策执行运动响应。然而，目前尚不清楚，除了这个作用之外，运动皮层本身是否也会影响反应选择。在这里，我们报告了使用 MEG 测量的运动皮层的活动波动，这些波动与选择内容无关，并在做出决定前几秒预测对视觉运动任务的反应。这些波动受到先前试验的反应的强烈影响，并预测在连续决策的反应替代方案之间切换的趋势。这种交替行为取决于先前反应中仍然存在的神经信号的大小。我们的结果揭示了感觉运动决策中的反应交替偏差。此外，他们认为运动皮层不仅仅是一个输出阶段，而是在感觉运动决策过程中塑造反应选择。 运动皮层根据感觉选择执行反应，但尚不清楚它是否也会影响反应选择。在这里，佩普和西格尔表明，在做出决策之前存在的运动皮层活动可以预测反应，并且该活动受到之前按下按钮的影响。
Our actions are constantly guided by decisions based on sensory information. The motor cortex is traditionally viewed as the final output stage in this process, merely executing motor responses based on these decisions. However, it is not clear if, beyond this role, the motor cortex itself impacts response selection. Here, we report activity fluctuations over motor cortex measured using MEG, which are unrelated to choice content and predict responses to a visuomotor task seconds before decisions are made. These fluctuations are strongly influenced by the previous trial's response and predict a tendency to switch between response alternatives for consecutive decisions. This alternation behaviour depends on the size of neural signals still present from the previous response. Our results uncover a response-alternation bias in sensorimotor decision making. Furthermore, they suggest that motor cortex is more than an output stage and instead shapes response selection during sensorimotor decision making. The motor cortex executes responses based on sensory choices, but it is unknown whether it also impacts response selection. Here, Pape and Siegel show that motor cortex activity present before decision making predicts responses and that this activity is influenced by previous button-presses.
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