Fundamental study of hot spot detectability in 3-dimensional positron emission tomography
Fundamental study of hot spot detectability in 3-dimensional positron emission tomography
复制标题
三维正电子发射断层扫描热点探测能力的基础研究
作者：
Hong Zhang;Tomio Inoue;S. Alyafei;M. Tian;N. Oriuchi;A. Ichikawa;K. Matsubara;K. Endo
本研究旨在探讨FDG-PET扫描中三维透射/发射（3D T/E）采集模式对小热病灶的检出能力。研究了靶点可探测性、靶点大小、靶点与非靶点摄取比值（T/N比值）和标准摄取值（SUV）的相关性。直径为4.4 ~ 36.9 mm的小热病灶位于圆柱体模中。采用二维透射/发射（2DT/E）扫描和三维T/E扫描获得T/N比分别为2.0、4.0、6.0、8.0、9.6、13.2、17.5、23.8和30.3的体模图像。在所有2D T/E和3D T/E采集模式获得的图像上，可以识别直径大于10.6 mm且实际T/N比范围为6.0至30.3的靶。2DTE和3DTE对小热靶的检出率相同（77.8%）。2D T/E图像靶区的T/N比与3D T/E图像靶区的T/N比相差30%~ 48.4%，靶区的SUV与3D T/E图像靶区的SUV相差不大。本研究表明，3D T/E扫描与2D T/E扫描具有相似的热点检测能力; 3D T/E和2D T/E扫描具有相同的使用SUV进行半定量分析的能力。这些结果有助于对3D T/E FDG-PET热病灶的诊断和认识。
The purpose of this study was to investigate the detectability of small hot lesions with the 3-dimensional transmission/emission (3D T/E) acquisition mode in FDG-PET scan. The correlation of target detectability, target size, target to non-target uptake ratio (T/N ratio) and standardized uptake value (SUV) were studied. Small hot lesions ranged from 4.4 mm to 36.9 mm in diameter were located in cylindrical phantom. The images of phantoms with a T/N ratio of 2.0, 4.0, 6.0, 8.0, 9.6, 13.2, 17.5, 23.8 and 30.3 were obtained with 2-dimensional transmission/emission (2D T/E) scan and 3D T/E scans. Targets in diameter more than 10.6 mm in diameter with an actual T/N ratio ranged from 6.0 to 30.3 could be identified on the images obtained with all the 2D T/E and 3D T/E acquisition modes. The detectability efficiency of small hot target in 2D T/E and 3D T/E scans was as same (77.8%). The T/N ratio of targets from 2D T/E images was 30% to 48.4% different to that from 3D T/E image, and the SUV of the target from the 2D T/E images was almost the same as that from 3D T/E images. This study revealed that 3D T/E scanning had similar hot spot detectability to 2D T/E scanning; 3D T/E and 2D T/E scanning had the same faculty for semiquantitative analysis using SUV. These findings may be helpful for the diagnosis and understanding of 3D T/E FDG-PET in hot lesion detection.
DOI：
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发表时间：
1991-04
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
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作者：
L. Strauss;P. Conti
通讯作者：
L. Strauss;P. Conti