Impact of modernization on urinary concentrations of arsenic, cadmium, lead, and selenium in rural residents of Northern Laos
Impact of modernization on urinary concentrations of arsenic, cadmium, lead, and selenium in rural residents of Northern Laos
复制标题
现代化对老挝北部农村居民尿液中砷、镉、铅和硒浓度的影响
DOI：
10.1002/ajhb.23685
复制
发表时间：
2021
影响因子：
2.9
通讯作者：
Umezaki Masahiro
中科院分区：
文献类型：
--
作者：
Mizuno Yuki;Masuoka Hiroaki;Kibe Mihoko;Kosaka Satoko;Natsuhara Kazumi;Hirayama Kazuhiro;Inthavong Nouhak;Kounnavong Sengchanh;Tomita Shinsuke;Umezaki Masahiro
目的：现代化对自给社会土著居民有毒重金属暴露和必需微量元素摄入的影响尚不清楚。我们评估了北方老挝的农村居民尿微量元素浓度，并研究了与modernization.MethodsA水平的关联进行了横断面研究，包括380名居民的北方老挝的三个村庄，具有不同的现代化水平。我们调查了341名参与者的一般特征，并测量了他们的体重和身高。砷，镉，铅，硒的浓度测定现场尿样电感耦合等离子体质谱法。我们研究了尿中微量元素浓度与现代化相关变量之间的关系（村庄、屋顶材料、财产指数[财产总数]和身体质量指数[BMI]），在调整了性别、年龄和吸烟状况后，采用多水平分析，以家庭为随机效应，而铅和硒的含量与以前报告的非污染地区或没有过量/缺乏的人群相比较低。我们观察到尿微量元素浓度与村庄水平现代化之间的关联：铅和硒浓度在现代化程度较高的村庄中较高，镉浓度在现代化程度最低的村庄中最高。尿砷浓度没有预测一个村庄的现代化水平，但我们观察到的村庄之间的显着差异。此外，尿硒浓度较高的参与者居住在更现代化的houses.ConclusionModernization的村庄可能会影响有毒重金属暴露和硒摄入量的北方老挝的农村居民。
ObjectivesThe impacts of modernization on toxic heavy metal exposure and essential trace element intake in indigenous populations of subsistence societies are unknown. We assessed urinary trace element concentrations in rural residents of Northern Laos and examined associations with levels of modernization.MethodsA cross‐sectional study was conducted comprising 380 residents of three villages in Northern Laos with different levels of modernization. We surveyed general characteristics and measured the weight and height of 341 participants. Arsenic, cadmium, lead, and selenium concentrations were measured in spot urine samples by inductively coupled plasma mass spectrometry. We examined associations between urinary trace element concentrations and variables related to modernization (village, roofing material, possessions index [total number of possessions], and body mass index [BMI]) using multilevel analyses with household as a random effect, after adjusting for sex, age, and smoking status.ResultsUrinary concentrations of arsenic and cadmium were high, while those of lead and selenium were low in comparison to previous reports of populations in non‐contaminated regions or without excess/deficiency. We observed associations between urinary trace element concentrations and village‐level modernization: lead and selenium concentrations were higher in more modernized villages and cadmium concentration was highest in the least modernized village. Urinary arsenic concentration was not predicted by the modernization level of a village, although we observed significant differences among villages. In addition, urinary selenium concentration was higher in participants inhabiting more modernized houses.ConclusionModernization of villages may impact toxic heavy metal exposure and selenium intake in rural residents of Northern Laos.
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DOI：
10.1515/cclm.1987.25.7.409
发表时间：
1987
期刊：
--
影响因子：
--
作者：
W. Wąsowicz;B. Zachara
通讯作者：
B. Zachara
影响因子：
3.5
作者：
GOYER, RA
通讯作者：
GOYER, RA
影响因子：
8.3
作者：
Berglund, Marika;Lindberg, Anna-Lena;Vahter, Marie
通讯作者：
Vahter, Marie
现代化的影响
DOI：
--
发表时间：
2015
期刊：
影响因子：
--
作者：
A. C. Muro;E. Rodríguez;C. Abate;F. Siñeriz
通讯作者：
F. Siñeriz
镉暴露和非暴露受试者尿中镉、铜和锌的排泄量，特别是 β2-微球蛋白和金属硫蛋白的尿排泄量
DOI：
--
发表时间：
2006
期刊：
影响因子：
--
作者：
中島 眞樹
通讯作者：
中島 眞樹