Basic investigation on acoustic velocity change imaging method for quantitative assessment of fat content in human liver
Basic investigation on acoustic velocity change imaging method for quantitative assessment of fat content in human liver
复制标题
声速变化成像法定量评价人体肝脏脂肪含量的基础研究
DOI：
--
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
H. Horinaka
中科院分区：
文献类型：
--
作者：
K. Mano;Shohei Tanigawa;M. Hori;D. Yokota;K. Wada;T. Matsunaka;H. Morikawa;H. Horinaka
脂肪肝是一种由脂肪在人体肝脏中过度积累而引起的疾病。脂肪肝的早期诊断非常重要，因为脂肪肝是与代谢综合征相关的主要标志物。我们已经提出了超声速度变化成像方法来诊断脂肪肝，利用这一事实，超声速度的温度依赖性是不同的水和脂肪。对于脂肪肝阶段的诊断，我们尝试了一个可行性研究的定量评估的脂肪含量在人类肝脏中使用我们的超声速度变化成像方法。实验结果表明，含猪油的组织模拟体模中的脂肪含量是由超声换能器与适当焦距的声透镜组成的环形加热超声换能器形成的平坦温度区中的超声速度变化来确定的。通过考虑我们使用热扩散方程的模拟结果，我们确定了该方法是否可以应用于脂肪肝评估的条件下，组织具有由血液流动引起的热弛豫效应。
Fatty liver is a disease caused by the excess accumulation of fat in the human liver. The early diagnosis of fatty liver is very important, because fatty liver is the major marker linked to metabolic syndrome. We already proposed the ultrasonic velocity change imaging method to diagnose fatty liver by using the fact that the temperature dependence of ultrasonic velocity is different in water and in fat. For the diagonosis of a fatty liver stage, we attempted a feasibility study of the quantitative assessment of the fat content in the human liver using our ultrasonic velocity change imaging method. Experimental results showed that the fat content in the tissue mimic phantom containing lard was determined by its ultrasonic velocity change in the flat temperature region formed by a circular warming ultrasonic transducer with an acoustic lens having an appropriate focal length. By considering the results of our simulation using a thermal diffusion equation, we determined whether this method could be applied to fatty liver assessment under the condition that the tissue had the thermal relaxation effect caused by blood flow.
一种用于超声热疗模型的可重复使用的灌注支持组织模拟材料。
影响因子：
3.8
作者：
Chin,RB;Madsen,EL;Zagzebski,JA;Jadvar,H;Wu,XK;Frank,GR
通讯作者：
Frank,GR