MRI-apparent localized deformation of the median nerve within the carpal tunnel during functional hand loading.
MRI-apparent localized deformation of the median nerve within the carpal tunnel during functional hand loading.
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DOI：
10.1007/s10439-013-0809-3
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发表时间：
2013-10
影响因子：
3.8
通讯作者：
Brown, Thomas D.
中科院分区：
文献类型：
--
作者：
Goetz, Jessica E.;Kunze, Nicole M.;Main, Erin K.;Thedens, Daniel R.;Baer, Thomas E.;Lawler, Ericka A.;Brown, Thomas D.
在MR图像中，腕管综合征（CTS）患者的正中神经经常比健康受试者更平坦。这项工作的目的是开发一种度量来量化局部正中神经变形，而不是全局神经扁平化，假设是局部正中神经变形将在CTS患者中升高。12例CTS患者和12名匹配的正常人进行了MRI扫描，在八个等距负载的手的条件。分析近端和远端隧道的2D横截面的神经横截面积、扁平率和隧道背侧的位置偏移。此外，计算了基于神经周长在边界周围0.5 mm长度的成角的新指标。局部变形度量能够检测CTS患者和健康受试者之间的差异，这些差异无法从扁平率中得到理解。在大多数手部活动中，正常受试者的局部变形神经边界的平均百分比高于CTS患者，尽管其整体形状更圆。CTS患者组中由于其与屈肌腱的相互作用而导致的局部神经变形较少，这表明CTS患者的神经可能不太顺应。
In MR images, the median nerve of carpal tunnel syndrome (CTS) patients frequently appears flatter than in healthy subjects. The purpose of this work was to develop a metric to quantify localized median nerve deformation rather than global nerve flattening, the hypothesis being that localized median nerve deformation would be elevated in CTS patients. Twelve patients with CTS and 12 matched normals underwent MRI scanning in eight isometrically loaded hand conditions. 2D cross sections of the proximal and distal tunnel were analyzed for nerve cross sectional area, flattening ratio, and a position shift to the dorsal side of the tunnel. Additionally, new metrics based on the angulation of the nerve perimeter in 0.5-mm lengths around the boundary were calculated. The localized deformation metrics were able to detect differences between CTS patients and healthy subjects that could not be appreciated from the flattening ratio. During most hand activities, normal subjects had a higher average percentage of locally deformed nerve boundary than did CTS patients, despite having a rounder overall shape. Less local nerve deformation in the CTS patient group resulting from its interaction with flexor tendons suggests that the nerve may be less compliant in CTS patients.
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DOI：
10.5435/00124635-200906000-00007
发表时间：
2009-06
期刊：
The Journal of the American Academy of Orthopaedic Surgeons
影响因子：
--
作者：
Keith MW;Masear V;Chung K;Maupin K;Andary M;Amadio PC;Barth RW;Watters WC 3rd;Goldberg MJ;Haralson RH 3rd;Turkelson CM;Wies JL
通讯作者：
Wies JL
影响因子：
10.6
作者：
Chan, TF;Vese, LA
通讯作者：
Vese, LA
影响因子：
5.5
作者：
Andreisek, Gustav;Crook, David W.;Weishaupt, Dominik
通讯作者：
Weishaupt, Dominik
影响因子：
19.7
作者：
MESGARZADEH, M;SCHNECK, CD;BONAKDARPOUR, A
通讯作者：
BONAKDARPOUR, A
影响因子：
4.4
作者：
Roberts, Michael D.;Sigal, Ian A.;Downs, J. Crawford
通讯作者：
Downs, J. Crawford