The distribution of biologically effective UV spectral irradiances received on a manikin face that cause erythema and skin cancer.
The distribution of biologically effective UV spectral irradiances received on a manikin face that cause erythema and skin cancer.
复制标题
人体模型面部收到的生物有效紫外线光谱辐照度的分布，会导致红斑和皮肤癌。
DOI：
10.1016/j.jphotobiol.2014.08.004
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Yang Liu
中科院分区：
文献类型：
--
作者：
F. Wang;Tiantian Ge;Q. Gao;Liwen Hu;Jiaming Yu;Yang Liu
太阳紫外线（UV）辐射是人类红斑和皮肤癌的主要原因，面部是风险最高的部位之一。生物有效的紫外线辐射（UVBE）是波长依赖性的，风险评估已被证明是基于接收到的紫外线辐射值。因此，本研究使用分光辐射计和头部人体模型测量面部皮肤暴露于UV光谱辐照度，通过作用光谱对其进行加权，以计算引起红斑（UVBEery）、非黑色素瘤（UVBEnon-mel）、人鳞状细胞癌（UVBEh-SCC）和DNA损伤（UVBEDNA-d）的UVBE。结果表明，在晴天，生物有效UVB和UVA辐射分别在65-73° SEA（8-9 UVI）和55-68° SEA（6-7 UVI）处有峰值。在10-30° SEA范围内，高度皮肤损伤波长均在300 nm处观察到。然而，在30-60°、60-81°和10-81° SEA范围内，对于UVBEery，高度皮肤损伤波长分别为300 nm、304 nm和300 nm;对于UVBEnon-mel，高度皮肤损伤波长分别为304 nm、306 nm和304 nm;对于UVBEh-SCC，高度皮肤损伤波长均为305 nm，对于UVBEDNA-d，高度皮肤损伤波长分别为302 nm和312 nm。
Solar ultraviolet (UV) radiation is a major cause of erythema and skin cancer in humans and the face is one of the highest risk sites. Biologically effective UV irradiation (UVBE) is wavelength-dependent, and risk assessment has been demonstrated based on the value of the received UV radiation. Therefore, this study measured the face skin exposure to UV spectral irradiance using a spectroradiometer and a head manikin, which were weighted by action spectra to calculate the UVBE that causes erythema (UVBEery), non-melanoma (UVBEnon-mel), human squamous cell cancer (UVBEh-SCC), and DNA damage (UVBEDNA-d). We determined that the biologically effective UVB and UVA irradiances on clear sky days had peak values at 65–73° SEA (8–9 UVI) and 55–68° SEA (6–7 UVI), respectively. In the 10–30° SEA range, the highly skin-damaging wavelengths were all observed at 300 nm. However, in the 30–60°, 60–81°, and 10–81° SEA ranges, the highly skin damaging wavelengths were 300 nm, 304 nm and 300 nm for UVBEery, respectively; 304 nm, 306 nm and 304 nm for UVBEnon-mel, respectively; all 305 nm for UVBEh-SCC, and two small peaks at 302 nm and 312 nm for UVBEDNA-d.
人类的定量致癌作用：马里兰州水工皮肤癌的太阳紫外线 B 剂量依赖性。
DOI：
10.1093/jnci/81.24.1910
发表时间：
1989
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Strickland,PT;Vitasa,BC;West,SK;Rosenthal,FS;Emmett,EA;Taylor,HR
通讯作者：
Taylor,HR
DOI：
10.1073/pnas.91.1.360
发表时间：
1994-01-04
影响因子：
11.1
作者：
NAKAZAWA, H;ENGLISH, D;YAMASAKI, H
通讯作者：
YAMASAKI, H
前瞻性女性队列中基底细胞癌的危险因素。
影响因子：
5.6
作者：
Hunter,DJ;Colditz,GA;Stampfer,MJ;Rosner,B;Willett,WC;Speizer,FE
通讯作者：
Speizer,FE