Community-based smoking cessation treatment for adults with high anxiety sensitivity: a randomized clinical trial.
Community-based smoking cessation treatment for adults with high anxiety sensitivity: a randomized clinical trial.
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高焦虑敏感性的成年人基于社区的戒烟治疗：一项随机临床试验。
DOI：
10.1111/add.15586
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发表时间：
2021-11
期刊：
影响因子：
6
通讯作者：
Garey, Lorra
中科院分区：
文献类型：
--
作者：
Smits, Jasper A. J.;Zvolensky, Michael J.;Rosenfield, David;Brown, Richard A.;Otto, Michael W.;Dutcher, Christina D.;Papini, Santiago;Freeman, Slaton Z.;DiVita, Annabelle;Perrone, Alex;Garey, Lorra
关键词：
患有焦虑症的人更容易吸烟，当他们试图戒烟时不太可能成功。焦虑敏感性可能是这两种现象的基础，比如焦虑敏感性高的人对内感受性痛苦的反应是回避。本研究旨在测试一项运动计划的有效性，该计划诱导内感受性痛苦，从而在安全的环境中产生对这种痛苦的耐受性。随机临床试验。美国德克萨斯州奥斯汀市的四个基督教青年会分支机构。参与者（N=150; 130例[86.7%]白色; 101例[67.3%]女性;法师=38.6，SDage=10.4）为成年人，每日吸烟，有高焦虑敏感性，有戒烟动机，报告没有定期中等强度运动。参与者被分配了一名YMCA私人教练，指导他们完成为期15周的干预有氧运动计划。被分配到个性化干预的参与者以其心率储备（HRR）的60-85%进行训练，而被分配到对照干预的参与者以其HRR的20-40%进行训练。两组的参与者都接受了标准的行为支持和尼古丁替代疗法。主要结局是6个月随访时经生物学验证的7天时点戒烟率（PPA）。61%的参与者在6个月随访时可用。假设随机缺失，个性化干预组6个月时的PPA高于对照干预组（27.6% vs. 14.8%; OR= 2.20，95%CI：[1.28，3.80]，P= 0.005）。两组的焦虑敏感性都有所下降，没有证据表明这在两组之间有差异。高强度的锻炼计划增加了高焦虑敏感性人群的戒烟率，但可能没有通过降低焦虑敏感性来实现。
People with anxiety disorders are more likely to smoke and less likely to succeed when they try to quit. Anxiety sensitivity may underlie both phenomena, such that people with high anxiety sensitivity react to interoceptive distress by avoidance. This study aimed to test the efficacy of an exercise program that induced interoceptive distress and thereby created tolerance to this distress in a safe environment. Randomized clinical trial. Four YMCA branches in Austin, Texas, United States. Participants (N=150; 130[86.7%] white; 101[67.3%] female; mage=38.6, SDage=10.4) were adult, daily smokers with high anxiety sensitivity motivated to quit smoking, who reported no regular moderate-intensity exercise. Participants were assigned a YMCA personal trainer who guided them through a 15-week intervention aerobic exercise program. Participants assigned to the personalized intervention trained at 60–85% of their heart rate reserve (HRR) whereas participants assigned to the control intervention trained at 20–40% of their HRR. Participants in both groups received standard behavioral support and nicotine replacement therapy. The primary outcome was biologically-verified 7-day point prevalence abstinence (PPA) at 6-month follow-up. Sixty-one percent of participants were available at the 6-month follow-up. PPA at 6 months was higher in the personalized intervention than the control intervention, (27.6% vs. 14.8%; OR=2.20,95% CI:[1.28,3.80],P=.005), assuming missing at random. Anxiety sensitivity declined in both groups with no evidence that this differed between groups. An exercise program of high intensity increased abstinence from smoking in people with high anxiety sensitivity but may not have done so by reducing anxiety sensitivity.
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