Mechanics of Microsporidian Polar Tube Firing.
Mechanics of Microsporidian Polar Tube Firing.
复制标题
微孢子虫极管发射的力学。
DOI:
10.1007/978-3-030-93306-7_9
复制
发表时间:
2022
影响因子:
--
通讯作者:
Bhabha,Gira
中科院分区:
文献类型:
--
作者:
Jaroenlak,Pattana;Usmani,Mahrukh;Ekiert,DamianC;Bhabha,Gira
As obligate intracellular parasites with reduced genomes, microsporidia must infect host cells in order to replicate and cause disease. They can initiate infection by utilizing a harpoon-like invasion organelle called the polar tube (PT). The PT is both visually and functionally a striking organelle and is a characteristic feature of the microsporidian phylum. Outside the host, microsporidia exist as transmissible, single-celled spores. Inside each spore, the PT is arranged as a tight coil. Upon germination, the PT undergoes a large conformational change into a long, linear tube and acts as a tunnel for the delivery of infectious cargo from the spore to a host cell. The firing process is extremely rapid, occurring on a millisecond timescale, and the emergent tube may be as long as 20 times the size of the spore body. In this chapter, we discuss what is known about the structure of the PT, the mechanics of the PT firing process, and how it enables movement of material from the spore body.
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影响因子:
6.1
作者:
J. Priestle
通讯作者:
J. Priestle
DOI:
--
发表时间:
1978
期刊:
影响因子:
--
作者:
A. Srinivasan;N. Yathindra
通讯作者:
N. Yathindra
影响因子:
5.6
作者:
A. Tulinsky;C. Park;E. Skrzypczak‐Jankun
通讯作者:
A. Tulinsky;C. Park;E. Skrzypczak‐Jankun
影响因子:
5.6
作者:
K. Watenpaugh;L. Sieker;L. H. Jensen
通讯作者:
L. H. Jensen
影响因子:
64.8
作者:
R. Balasubramanian
通讯作者:
R. Balasubramanian