Branched thalamic afferents: what are the messages that they relay to the cortex?
Branched thalamic afferents: what are the messages that they relay to the cortex?
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DOI：
10.1016/j.brainresrev.2010.08.001
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发表时间：
2011-01-07
影响因子：
--
通讯作者：
Sherman SM
中科院分区：
文献类型：
--
作者：
Guillery RW;Sherman SM
许多将信息传递到丘脑再传递到大脑皮层的轴突，都以一种从高尔基体制备物中早就知道的模式分支。它们将一个分支送到丘脑，另一个送到脑干或脊髓的运动中心。因为丘脑分支必然携带运动指令的副本，所以它们的信息具有传出副本的特性。也就是说，它们可以被认为提供了关于即将发生的指令的可靠信息，这些指令有助于产生对受体的输入变化的运动，从而允许神经中枢补偿这些输入变化。我们考虑如何感觉通路，如内侧丘系，脊髓丘脑束或视束也可以被看作是一个通路的传出副本。丘脑的上行输入和皮层输入与运动输出建立了直接联系，这些直接联系创造了感觉运动关系，为皮层提供了一个较低回路的活动模型，并将行为的感觉和运动方面联系得更紧密，比运动输出具有单一的中央起源所预期的要紧密得多。这些跨丘脑连接模式不同于经典模型的单独的神经通路进行传出副本的行动产生的更高的水平，并介绍了一些不同的功能的可能性。
Many of the axons that carry messages to the thalamus for relay to the cerebral cortex are branched in a pattern long known from Golgi preparations. They send one branch to the thalamus and the other to motor centers of the brainstem or spinal cord. Because the thalamic branches necessarily carry copies of the motor instructions their messages have the properties of efference copies. That is, they can be regarded as providing reliable information about impending instructions contributing to movements that will produce changes in inputs to receptors, thus allowing neural centers to compensate for these changes of input. We consider how a sensory pathway like the medial lemniscus, the spinothalamic tract or the optic tract can also be seen to act as a pathway for an efference copy. The direct connections that ascending and cortical inputs to the thalamus also establish to motor outputs create sensorimotor relationships that provide cortex with a model of activity in lower circuits and link the sensory and the motor sides of behavior more tightly than can be expected from motor outputs with a single, central origin. These transthalamic connectional patterns differ from classical models of separate neural pathways for carrying efference copies of actions generated at higher levels, and introduce some different functional possibilities.
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影响因子：
1.8
作者：
Berman, Rebecca;Colby, Carol
通讯作者：
Colby, Carol
DOI：
10.1073/pnas.170278697
发表时间：
2000-08-15
影响因子：
11.1
作者：
Cox, CL;Denk, W;Svoboda, K
通讯作者：
Svoboda, K
影响因子：
2.9
作者：
AKINTUNDE, A;BUXTON, DF
通讯作者：
BUXTON, DF
影响因子：
2.5
作者：
KULTASILINSKY, K;ILINSKY, IA
通讯作者：
ILINSKY, IA
影响因子：
2.5
作者：
Colby, CL;Duhamel, JR;Goldberg, ME
通讯作者：
Goldberg, ME