Packaging and coating materials for implantable devices
Packaging and coating materials for implantable devices
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植入式器械的包装和涂层材料
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
P. Vadgama
中科院分区：
文献类型：
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作者：
J. Wasikiewicz;N. Roohpour;P. Vadgama
摘要：可植入微电子机械系统(MEMS)以前所未有的小型化和内部功能复杂性提供了一种在体内进行传感和驱动的宝贵手段。然而，功能可能会受到水分吸收和体内不利相互作用的影响。因此，包装材料起到了阻挡相的作用，用于控制溶质的交换，并为MEMS器件提供生物兼容的表面。本章介绍了一系列用于保护体内MEMS器件的涂层。表面修饰和生物活性物质释放被描述为提高生物相容性和减少表面污垢的策略。包装材料的各种机械、渗透性和化学特性与延长MEMS植入物的寿命有关，并对当代包装材料进行了描述。
Abstract: Implantable micro-electromechanical systems (MEMS) offer a valuable means of sensing and actuation within the body at unprecedented levels of miniaturisation and internal functional complexity. However, function can be compromised by moisture uptake and adverse interactions within the body. Consequently, packaging materials serve as barrier phases for controlling exchange of solutes and furnishing biocompatible surfaces for MEMS devices. This chapter covers a range of coatings used to protect MEMS devices in the body. Surface modification and bioactive agent release are described as strategies for enhancing biocompatibility and reducing surface fouling. The full range of mechanical, permeability and chemical features of packaging materials are involved in the extended survival of MEMS implants and are described for contemporary packaging materials.
影响因子：
12.6
作者：
RATNER, BD
通讯作者：
RATNER, BD
影响因子：
4.9
作者：
Xu, RJ;Manias, E;Runt, J
通讯作者：
Runt, J
影响因子：
7.4
作者：
ESPADASTORRE, C;MEYERHOFF, ME
通讯作者：
MEYERHOFF, ME