Multimodal imaging of the course of retinal changes in acute posterior multifocal placoid pigment epitheliopathy with bilateral retinal detachment: a case report.
Multimodal imaging of the course of retinal changes in acute posterior multifocal placoid pigment epitheliopathy with bilateral retinal detachment: a case report.
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急性后部多灶性鳞状色素上皮病伴双侧视网膜脱离视网膜变化过程的多模态成像：一例报告
DOI：
10.1186/s12886-022-02624-3
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发表时间：
2022-10-07
影响因子：
2
通讯作者：
Cai, Shan-Jun
中科院分区：
文献类型：
--
作者：
Su, Gang;Meng, Jia;Li, Hong;Cai, Shan-Jun
关键词：
报告1例罕见的急性后极部多灶性扁平状色素上皮病变（APMPPE）合并浆液性视网膜脱离、视乳头水肿及视网膜血管炎的病例。
一名19岁男性，主诉双眼出现漂浮物伴视力下降4天。右眼和左眼的最佳矫正视力分别为1.1和0.9（logMAR）。双眼玻璃体中可见炎性细胞悬浮，黄斑附近可见多个黄白色病灶，伴视网膜神经上皮脱离。左眼视盘肿胀，边界模糊。光学相干断层扫描（OCT）显示双眼视网膜脱离。患者接受口服泼尼松治疗。1周后，OCT显示双眼黄斑下视网膜液吸收，双眼视力提高至0.1（logMAR）。在随后28个月的随访中，眼底荧光血管造影和OCT显示双眼广泛且进行性的色素上皮萎缩，由于持续性视网膜血管炎，右眼还出现视网膜血管灌注异常。尽管患者双眼视力仍维持在0.1（logMAR）。
在本APMPPE合并浆液性视网膜脱离、视乳头水肿及视网膜血管炎的病例中，通过多模态成像进一步证实病变位于脉络膜，而色素上皮病变为继发性改变。
To report a rare case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) with a combination of serous retinal detachment, papilledema, and retinal vasculitis. A 19-year-old male complained of floaters in both eyes with decreased vision for 4 days. The best corrected visual acuity of the right eye and the left eye were 1.1 and 0.9 (logMAR), respectively. In both eyes, inflammatory cells can be seen suspended within the vitreous, multiple yellow/white lesions can be seen near the macula, and retinal neuroepithelial detachment. Swelling of the optic disc with blurring of the disc margins, in the left eye. Optical coherence tomography (OCT): showed retinal detachment in both eyes. The patient received oral prednisone treatment. 1 week later, OCT showed absorption of subretinal fluid in the macula of both eyes his binocular vision improved to 0.1 (logMAR). During the subsequent 28-month follow-up, fundus fluorescein angiography and OCT revealed extensive and progressive pigment epithelial atrophy in both eyes, and abnormal retinal vascular perfusion in the right eye due to persistent retinal vasculitis. Although the patient's binocular visual acuity remained at 0.1 (logMAR). In the present case of APMPPE with a combination of serous retinal detachment, papilledema, and retinal vasculitis, through the multimodal imaging, further confirming that the lesions were located in the choroid, while the pigment epithelial lesions were secondary changes.
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