Comparison of 7 T and 3 T vessel wall MRI for the evaluation of intracranial aneurysm wall.

Comparison of 7 T and 3 T vessel wall MRI for the evaluation of intracranial aneurysm wall.
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7T与3T血管壁MRI评估颅内动脉瘤壁的比较

DOI:
10.1007/s00330-021-08331-9
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发表时间:
2022-04
期刊:
影响因子:
5.9
通讯作者:
--
中科院分区:
医学2区
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--
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比较 7 和 3 T 血管壁成像的颅内动脉瘤壁可见度和厚度量化,并评估动脉瘤大小和壁厚度之间的关联。前瞻性招募 29 名患有 29 个未破裂颅内动脉瘤的患者,进行 3T 和 7T 的 3D T1 加权血管壁 MRI,各向同性分辨率分别为 0.53 mm (3 T) 和 0.4 mm (7 T)。两名神经放射科医生独立评估管壁可见度(0-5 Likert 量表),使用半自动全宽半最大值方法量化表观管壁厚度 (AWT),计算管壁清晰度,并测量管壁与管腔对比度 (CRwall/管腔)。本研究包括 24 名患有 24 个动脉瘤的患者。 7 T 的动脉瘤壁可见度明显优于 3 T(3.6 ± 1.1 vs 2.7 ± 0.8,p = 0.003)。 3 T 和 7 T 测量的 AWT 具有良好的相关性(平均 r = 0.63 ± 0.19)。然而,3 T 上的 AWT 比 7 T 上的 AWT 厚 15%(0.52 ± 0.07 mm 与 0.45 ± 0.05 mm,p < 0.001)。 7 T 上的壁清晰度比 3 T 上的壁清晰度高 57%(1.95 ± 0.32 mm−1 与 1.24 ± 0.15 mm−1,p < 0.001)。 3 T 和 7 T 上的 CRwall/lumen 具有可比性 (p = 0.424)。 7 T 上的 AWT 与动脉瘤大小呈正相关(囊状:r = 0.58,q = 0.046;梭状:r = 0.67,q = 0.049)。 7 T 提供了更好的颅内动脉瘤壁可视化,其清晰度比 3 T 更高。相对于 7 T,3 T 高估了壁厚度。动脉瘤壁厚度与动脉瘤大小呈正相关。 7 T MRI 是一种很有前景的体内评估动脉瘤壁的工具。
To compare the visibility of intracranial aneurysm wall and thickness quantification between 7 and 3 T vessel wall imaging and evaluate the association between aneurysm size and wall thickness. Twenty-nine patients with 29 unruptured intracranial aneurysms were prospectively recruited for 3D T1-weighted vessel wall MRI at both 3 T and 7 T with 0.53 mm (3 T) and 0.4 mm (7 T) isotropic resolution, respectively. Two neuroradiologists independently evaluated wall visibility (0–5 Likert scale), quantified the apparent wall thickness (AWT) using a semi-automated full-width-half-maximum method, calculated wall sharpness, and measured the wall-to-lumen contrast ratio (CRwall/lumen). Twenty-four patients with 24 aneurysms were included in this study. 7 T achieved significantly better aneurysm wall visibility than 3 T (3.6 ± 1.1 vs 2.7 ± 0.8, p = 0.003). AWT measured on 3 T and 7 T had a good correlation (averaged r = 0.63 ± 0.19). However, AWT on 3 T was 15% thicker than that on 7 T (0.52 ± 0.07 mm vs 0.45 ± 0.05 mm, p < 0.001). Wall sharpness on 7 T was 57% higher than that on 3 T (1.95 ± 0.32 mm−1 vs 1.24 ± 0.15 mm−1, p < 0.001). CRwall/lumen on 3 T and 7 T was comparable (p = 0.424). AWT on 7 T was positively correlated with aneurysm size (saccular: r = 0.58, q = 0.046; fusiform: r = 0.67, q = 0.049). 7 T provides better visualization of intracranial aneurysm wall with higher sharpness than 3 T. 3 T overestimates the wall thickness relative to 7 T. Aneurysm wall thickness is positively correlated with aneurysm size. 7 T MRI is a promising tool to evaluate aneurysm wall in vivo.
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发表时间: 2016-07
期刊: AJNR. American journal of neuroradiology
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