NIR fluorescence imaging and treatment for cancer immunotherapy.
NIR fluorescence imaging and treatment for cancer immunotherapy.
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DOI：
10.1136/jitc-2022-004936
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发表时间：
2022-07
影响因子：
10.9
通讯作者：
中科院分区：
文献类型：
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作者：
癌症免疫疗法已成为最强大的抗癌疗法之一。然而，关于肿瘤与免疫系统之间相互作用的细节是复杂的，并且仍然知之甚少。光学荧光成像是一种允许荧光标记的免疫细胞可视化并在免疫治疗期间监测免疫反应的技术。为此，近红外（NIR）光已被应用于光学荧光成像，因为它相对安全且简单，没有危险的电离辐射，并且比可见荧光对生物体的组织渗透相对更深。在这篇综述中，我们讨论了国家的最先进的近红外光学成像技术在癌症免疫治疗中观察的动态，疗效和免疫组分在活生物体中的反应。生物成像标记技术的使用将使我们了解免疫系统是如何启动和最终发展的。
Cancer immunotherapy has emerged as one of the most powerful anticancer therapies. However, the details on the interaction between tumors and the immune system are complicated and still poorly understood. Optical fluorescence imaging is a technique that allows for the visualization of fluorescence-labeled immune cells and monitoring of the immune response during immunotherapy. To this end, near-infrared (NIR) light has been adapted for optical fluorescence imaging because it is relatively safe and simple without hazardous ionizing radiation and has relatively deeper tissue penetration into living organisms than visible fluorescence light. In this review, we discuss state-of-the-art NIR optical imaging techniques in cancer immunotherapy to observe the dynamics, efficacy, and responses of the immune components in living organisms. The use of bioimaging labeling techniques will give us an understanding of how the immune system is primed and ultimately developed.
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影响因子：
8
作者：
Damalakiene L;Karabanovas V;Bagdonas S;Valius M;Rotomskis R
通讯作者：
Rotomskis R
影响因子：
4
作者：
Balana, Carmen;Capellades, Jaume;Alameda, Francesc
通讯作者：
Alameda, Francesc
影响因子：
17.1
作者：
Fischbach MA;Bluestone JA;Lim WA
通讯作者：
Lim WA
与激发激光器相匹配的短波红外多胸荧光团可实时实时非侵入性，多色在体内成像。
影响因子：
21.8
作者：
Cosco ED;Spearman AL;Ramakrishnan S;Lingg JGP;Saccomano M;Pengshung M;Arús BA;Wong KCY;Glasl S;Ntziachristos V;Warmer M;McLaughlin RR;Bruns OT;Sletten EM
通讯作者：
Sletten EM
影响因子：
38.3
作者：
通讯作者：
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