Genotype-specific responses of fluctuating asymmetry and of preadult survival to the effects of lead and temperature stress in Drosophila melanogaster.
Genotype-specific responses of fluctuating asymmetry and of preadult survival to the effects of lead and temperature stress in Drosophila melanogaster.
复制标题
果蝇中波动不对称性和成体前生存对铅和温度应激影响的基因型特异性反应。
DOI：
10.1016/s0269-7491(03)00238-0
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
PoncedeLeon,Claudia
中科院分区：
文献类型：
--
作者：
Polak,Michal;Kroeger,DavidE;Cartwright,IainL;PoncedeLeon,Claudia
虽然波动不对称性（FA）随着暴露于某些类型的环境应激源（如极端温度）而增加，但对相互作用的影响（例如，协同作用）之间的已知来源的环境压力对FA。这种相互作用的影响，以及基因型与环境相互作用的程度的知识，是预测FA作为环境污染的生物指示剂的有用性的根本重要性。我们测试的协同效应之间的FA升高的温度和暴露于铅，并检查FA的反应，同时在四个遗传株的果蝇已知不同的程度的发展不稳定性，并推测在他们的缓冲能力。在不存在重金属的情况下，刷毛FA随温度而增加，但在存在铅的情况下，高温（30 °C）下的FA降低到与低温（25 °C）下的FA相似或更低的水平。这种温度与铅的相互作用在统计学上是显著的，但矛盾的是，温度的破坏性影响似乎在重金属的存在下减弱。在任何情况下，有一个显着的影响，铅刚毛脂肪酸，尽管记录的重金属的苍蝇同化，并在任何情况下是基因型与环境的相互作用显着。而铅治疗没有影响生存，生存减少在高温下，但显着，所以只有在一个遗传菌株（俄勒冈-R）。有没有生存和FA之间的关系，在整个压力处理线内。因此，任何不成比例的压力诱导的死亡率在发展不稳定类（发展选择）是不太可能偏见的FA结果。我们的研究结果强调了在基于FA的生物监测能够负责任和有效地实施之前，需要独立复制重要的发现。结果呼吁谨慎使用FA作为压力的生物标志物，因为压力因素可能会以复杂和不可预测的方式相互作用，这可能会导致错误的结论，真实的水平的压力存在于现场人群，在过度简单化的假设下，压力因素将采取加性行动，以增加FA。
Although fluctuating asymmetry (FA) increases with exposure to certain types of environmental stressors such as temperature extremes, relatively little is known about the effects of interaction (e.g., synergism) between known sources of environmental stress on FA. Knowledge of such interaction effects, and of the magnitude of genotype-by-environment interaction, are of fundamental importance toward predicting the usefulness of FA as a bioindicator of environmental pollution. We tested for synergistic effects on FA between elevated temperature and exposure to lead, and examined FA responses simultaneously in four genetic strains of Drosophila melanogaster known to differ in their degree of developmental instability, and presumably in their buffering capacity. In the absence of heavy metal, bristle FA increased with temperature, but in the presence of lead, FA at high temperature (30 °C) was reduced to levels similar, or below, that at lower temperature (25 °C). This temperature by lead interaction was statistically significant, but paradoxical in that the disruptive effects of temperature appeared to be attenuated in the presence of the heavy metal. In no case was there a significant effect of lead on bristle FAs, despite documented assimilation of heavy metal by flies, and in no case was the genotype by environment interaction significant. Whereas lead treatment did not influence survival, survival was reduced at the high temperature, but significantly so only in one genetic strain (Oregon-R). There was no relationship between survival and FA across stress treatments within lines. Thus, any disproportionate stress-induced mortality in developmentally unstable classes (developmental selection) was unlikely to bias the FA results. Our results underscore the need for independent replication of significant findings before FA-based biomonitoring can be responsibly and effectively implemented. The results call for caution in using FA as a biomarker of stress, because stress factors may interact in complex and unpredictable ways, which could result in erroneous conclusions about real levels of stress present in field populations, under the unduly simplistic assumption that stress factors will act additively to increase FA.
登录
查看更多内容
国家与人民之间的法律链接问题
DOI：
--
发表时间：
1932
期刊：
影响因子：
--
作者：
W. Ludwig
通讯作者：
W. Ludwig
DOI：
--
发表时间：
2004
期刊：
影响因子：
--
作者：
Martin L. Lalumière
通讯作者：
Martin L. Lalumière
母亲的体外寄生会导致儿子出现更高的位置波动不对称性：对性选择的影响
影响因子：
2.9
作者：
M. Polák
通讯作者：
M. Polák
极端温度对果蝇和果蝇表型变异和发育稳定性的影响
DOI：
--
发表时间：
1997
期刊：
影响因子：
--
作者：
A. Imasheva;V. Loeschcke;L. Zhivotovsky;O. Lazebny
通讯作者：
O. Lazebny
DOI：
10.1520/stp1179-eb
发表时间：
1993
期刊：
--
影响因子：
--
作者：
W. Landis;J. S. Hughes;M. Lewis
通讯作者：
W. Landis;J. S. Hughes;M. Lewis