Advancing analytical algorithms and pipelines for billions of microbial sequences.
Advancing analytical algorithms and pipelines for billions of microbial sequences.
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DOI:
10.1016/j.copbio.2011.11.028
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发表时间:
2012-02
影响因子:
7.7
通讯作者:
Knight, Rob
中科院分区:
文献类型:
--
作者:
Gonzalez, Antonio;Knight, Rob
The vast number of microbial sequences resulting from sequencing efforts using new technologies require us to re-assess currently available analysis methodologies and tools. Here we describe trends in the development and distribution of software for analyzing microbial sequence data. We then focus on one widely used set of methods, dimensionality reduction techniques, which allow users to summarize and compare these vast datasets. We conclude by emphasizing the utility of formal software engineering methods for development of computational biology tools, and the need for new algorithms for comparing microbial communities. Such large-scale comparisons will allow us to fulfill the dream of rapid integration and comparison of microbial sequence data sets, in a replicable analytical environment, in order to describe the microbial world we inhabit.
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影响因子:
4.4
作者:
Bartram, Andrea K.;Lynch, Michael D. J.;Neufeld, Josh D.
通讯作者:
Neufeld, Josh D.
影响因子:
3
作者:
Angiuoli SV;Matalka M;Gussman A;Galens K;Vangala M;Riley DR;Arze C;White JR;White O;Fricke WF
通讯作者:
Fricke WF
影响因子:
48
作者:
Kuczynski, Justin;Liu, Zongzhi;Lozupone, Catherine;McDonald, Daniel;Fierer, Noah;Knight, Rob
通讯作者:
Knight, Rob
影响因子:
2.1
作者:
Lauber CL;Zhou N;Gordon JI;Knight R;Fierer N
通讯作者:
Fierer N
DOI:
10.1073/pnas.1000080107
发表时间:
2011-03-15
影响因子:
11.1
作者:
Caporaso, J. Gregory;Lauber, Christian L.;Knight, Rob
通讯作者:
Knight, Rob