A comprehensive testing protocol for macro-scale mechanical characterization of knee articular cartilage with documented experimental repeatability.
A comprehensive testing protocol for macro-scale mechanical characterization of knee articular cartilage with documented experimental repeatability.
复制标题
膝关节软骨的宏观机械表征的综合测试方案，具有记录的实验可重复性。
DOI：
10.1016/j.jmbbm.2020.104025
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发表时间：
2020-12
影响因子：
3.9
通讯作者：
Erdemir A
中科院分区：
文献类型：
--
作者：
Chokhandre S;Erdemir A
关节软骨力学已经通过各种方法和力学表征策略得到了广泛的研究。然而，检测方案可能变化很大，很难重现，特别是对于特定样本的分析。为了在协调有限元分析中可靠地使用，详细的测试协议知识是重要的。这项研究提出了一种详细的、稳健的软骨测试程序--具有多个区域和每个样本的重复性数据。标本取自人身体膝关节的股骨、胫骨和膝盖骨，进行无侧限压缩、约束压缩和单轴拉伸试验。每项测试都重复了三次。测试协议提供弹性的和时间相关的表征数据。结果，例如，无侧限压缩下的平衡弹模0.28(0.0024)Mpa表明变异性被很好地控制，并且这里介绍的方案(S)可以产生可重复的特定样本的数据。据作者所知，这是首次报道对多区域膝关节软骨表征的实验程序进行深入的不确定性评估的研究。
Articular cartilage mechanics has been extensively studied with various approaches and mechanical characterization strategies. However testing protocols can be highly varying and difficult to reproduce, particularly for specimen-specific analyses. Detailed knowledge of testing protocols is important for reliable use in concordant finite element analyses. This study presents a detailed, robust procedure for cartilage testing—with multiple regions and per specimen repeatability data. Samples were taken from femur, tibia and patella of a human cadaver knee and tested in unconfined compression, confined compression and uniaxial tension. Each test was repeated three times. The testing protocols provide elastic and time dependent characterization data. Results, for example equilibrium modulus of 0.28 (0.0024) MPa for patella under unconfined compression indicate that variability is well controlled and that protocol(s) presented here can generate repeatable specimen-specific data. As per the authors’ knowledge this is the first study to report in-depth uncertainty assessment of the experimental procedures for multi-region knee cartilage characterization.
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影响因子：
--
作者：
Kazemi M;Dabiri Y;Li LP
通讯作者：
Li LP
影响因子：
2.4
作者：
Cheng, Shaokoon;Clarke, Elizabeth C.;Bilston, Lynne E.
通讯作者：
Bilston, Lynne E.
影响因子：
2.4
作者：
BLANKEVOORT, L;KUIPER, JH;GROOTENBOER, HJ
通讯作者：
GROOTENBOER, HJ
影响因子：
2.4
作者：
Bursac, PM;Obitz, TW;Stamenovic, D
通讯作者：
Stamenovic, D
影响因子：
3.9
作者：
Ahsanizadeh S;Li L
通讯作者：
Li L