Genes and genomes: chromosome bands – flavours to savour
Genes and genomes: chromosome bands – flavours to savour
复制标题
基因和基因组:染色体带——品味
DOI:
--
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发表时间:
1993
期刊:
影响因子:
--
通讯作者:
W. Bickmore
中科院分区:
文献类型:
--
作者:
J. Craig;W. Bickmore
The mammalian chromosome is longitudinally heterogeneous in structure and function and this is the basis for the specific banding patterns produced by various chromosome staining techniques. The two most frequently used techniques are G, or Giemsa banding and R, or reverse banding. Each type of stained band is characterised by variations in gene density, time of replication, base composition, density of repeat sequences, and chromatin packaging. It is increasingly apparent that R and G bands, which are complementary to each other, represent separate compartments of the euchromatic human genome, with R bands containing the vast majority of genes. R bands are also more GC-rich, contain a higher density of Alu repeats, and replicate earlier in S phase, than G bands. These properties may be interdependent and may have coevolved.
影响因子:
4.4
作者:
Gessler,M;Bruns,GA
通讯作者:
Bruns,GA
DOI:
10.1002/j.1460-2075.1990.tb08076.x
发表时间:
1990
期刊:
The EMBO journal
影响因子:
--
作者:
Gardiner,K;Horisberger,M;Kraus,J;Tantravahi,U;Korenberg,J;Rao,V;Reddy,S;Patterson,D
通讯作者:
Patterson,D