Genotyping Cyclospora cayetanensis From Multiple Outbreak Clusters With An Emphasis on a Cluster Linked to Bagged Salad Mix-United States, 2020.
Genotyping Cyclospora cayetanensis From Multiple Outbreak Clusters With An Emphasis on a Cluster Linked to Bagged Salad Mix-United States, 2020.
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DOI：
10.1093/infdis/jiab495
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发表时间：
2022-06-15
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--
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环孢子虫病是一种由食源性寄生虫卡耶塔环孢子虫引起的腹泻病。美国每年报告的病例不断增加，促使开发基因分型工具来帮助集群检测。最近开发的基于 8 个遗传标记的环孢子虫基因分型系统应用于 2020 年环孢子虫病高峰期收集的临床样本，有助于评估其流行病学效用。虽然该系统表现良好并有助于为流行病学调查提供信息，但支持纳入其他标记以改进聚类检测。因此，已经开始研究以确定额外的标记来提高性能。 CDC 开发的环孢子虫分型方法用于补充 2020 年环孢子虫病爆发的调查。该工具检测到与 2020 年最大规模环孢子虫病爆发相关的簇等。还强调了改进该工具的机会。
Cyclosporiasis is a diarrheal illness caused by the foodborne parasite Cyclospora cayetanensis. Annually reported cases have been increasing in the United States prompting development of genotyping tools to aid cluster detection. A recently developed Cyclospora genotyping system based on 8 genetic markers was applied to clinical samples collected during the cyclosporiasis peak period of 2020, facilitating assessment of its epidemiologic utility. While the system performed well and helped inform epidemiologic investigations, inclusion of additional markers to improve cluster detection was supported. Consequently, investigations have commenced to identify additional markers to enhance performance. A Cyclosporagenotyping method developed at CDC was used to complement investigations of cyclosporiasis outbreaks in 2020. The tool detected clusters associated with the largest cyclosporiasis outbreak from 2020, among others. Opportunities for refinement of the tool were also highlighted.
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影响因子：
33.9
作者：
Tack, Danielle M.;Ray, Logan;Payne, Daniel C.
通讯作者：
Payne, Daniel C.
影响因子：
4.2
作者：
Barratt J;Houghton K;Richins T;Straily A;Threlkel R;Bera B;Kenneally J;Clemons B;Madison-Antenucci S;Cebelinski E;Whitney BM;Kreil KR;Cama V;Arrowood MJ;Qvarnstrom Y
通讯作者：
Qvarnstrom Y
DOI：
10.1128/genomea.01324-15
发表时间：
2015-11-19
期刊：
Genome announcements
影响因子：
--
作者：
Qvarnstrom Y;Wei-Pridgeon Y;Li W;Nascimento FS;Bishop HS;Herwaldt BL;Moss DM;Nayak V;Srinivasamoorthy G;Sheth M;Arrowood MJ
通讯作者：
Arrowood MJ
影响因子：
4.2
作者：
Nascimento, Fernanda S.;Barratt, Joel;Qvarnstrom, Yvonne
通讯作者：
Qvarnstrom, Yvonne
影响因子：
4.3
作者：
Campbell EM;Boyles A;Shankar A;Kim J;Knyazev S;Cintron R;Switzer WM
通讯作者：
Switzer WM