Superposition of arteriolar vasomotion waves and regulation of blood flow in skeletal muscle microcirculation.
Superposition of arteriolar vasomotion waves and regulation of blood flow in skeletal muscle microcirculation.
复制标题
小动脉血管舒缩波的叠加与骨骼肌微循环血流的调节。
DOI：
--
复制
发表时间：
1990
影响因子：
--
通讯作者：
L. Donato
中科院分区：
文献类型：
--
作者：
A. Colantuoni;S. Bertuglia;G. Coppini;L. Donato
在皮肤肌肉微循环的叙利亚仓鼠，节奏的直径变化进行了研究沿着的小动脉网络，在正常氧条件下，在休息。在动物背部皮肤中植入一个涂有聚四氟乙烯的铝腔。采用活体显微镜技术观察微循环。通过计算机辅助方法确定血管直径。用快速傅立叶变换和自回归模型对血管运动记录进行功率谱分析。为了确定血管运动波形扩展，使用改进的周期图方法（FFT）计算交叉频谱数据（振幅和相位）。根据Strahler的方法对小动脉进行分类。1级血管（直径：7.50 +/- 1.16微米）显示出最高频率，4-15次循环/min，振幅百分比在60- 100%范围内。2级和3级小动脉具有中频，振幅分别在50- 100%和15- 50%的范围内。最大的4级血管（直径：28.97 +/- 9.55微米）的频率最低，为0.3-3 cpm，振幅范围为5- 20%。在大多数网络中，互相关分析揭示了两组频率分量。低频群由4、3级血管向下游扩散。高频成分从1级和2级小动脉向上游传输。因此，波形的复杂叠加由沿着微血管沿着的离散点的活动引起。总之，骨骼肌微循环中小动脉直径的节律性变化调节毛细血管单位中的血流分布并控制组织氧合。
In skin muscle microcirculation of Syrian hamsters, rhythmic diameter changes were studied along the arteriolar network, under normoxic conditions, at rest. A teflon coated-aluminum chamber was implanted in the dorsum skin of animals. The microcirculation was investigated using intravital microscopy technique. Vessel diameters were determined by a computer-assisted method. Power spectrum analysis of vasomotion recordings was carried out with Fast Fourier Transform and Autoregressive modelling. To determine vasomotion waveform spreading, cross-spectral data (amplitude and phase) were computed, using the modified periodogram method (FFT). The arterioles were classified according to Strahler's method. Order 1 vessels (diameter: 7.50 +/- 1.16 microns) showed the highest frequency, 4-15 cycles per min, and percentage amplitude in the range 60-100%. Order 2 and 3 arterioles had intermediate frequencies, and amplitude in the range 50-100%, and 15-50%, respectively. The largest order 4 vessels (diameter: 28.97 +/- 9.55 microns) had the lowest frequency, 0.3-3 cpm, and amplitude in the range 5-20%. In most networks, cross-correlation analysis revealed two groups of frequency components. Low frequency group was propagated from order 4 and 3 vessels downstream. High frequency components were transmitted upstream from order 1 and 2 arterioles. Therefore, a complex superposition of waveforms resulted from the activity of discrete points along the microvasculature. In conclusion, rhythmic diameter changes of arterioles in skeletal muscle microcirculation regulate blood flow distribution in capillary units and control tissue oxygenation.
DOI：
10.1152/ajpheart.1987.253.3.h568
发表时间：
1987
期刊：
The American journal of physiology
影响因子：
--
作者：
Meyer,JU;Lindbom,L;Intaglietta,M
通讯作者：
Intaglietta,M