Ossification and increased bone mineral density with zoledronic acid in a patient with lung adenocarcinoma: A case report.
Ossification and increased bone mineral density with zoledronic acid in a patient with lung adenocarcinoma: A case report.
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DOI：
10.3892/etm.2014.1914
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发表时间：
2014-10
影响因子：
2.7
通讯作者：
Hizawa N
中科院分区：
文献类型：
--
作者：
Kurishima K;Ohara G;Kagohashi K;Takayashiki N;Tamura T;Shiozawa T;Miyazaki K;Kawaguchi M;Satoh H;Hizawa N
尚未报告唑来膦酸（ZA）治疗后骨转移部位骨化和骨密度（BMD）增加的病例。目前的研究提出了一个65岁的患者肺腺癌和骨转移的腰椎和股骨。在用ZA治疗和骨转移部位的照射后，在转移部位实现骨化和BMD增加。尽管有骨转移，但患者能够维持正常的生活方式超过两年。因此，由于ZA治疗被证明可以改善患者的生活质量，医生应该考虑这种治疗策略，特别是对于承重骨转移的治疗。
Cases of ossification and increased bone mineral density (BMD) at sites of bone metastasis following zoledronic acid (ZA) treatment have not been reported. The current study presents the case of a 65-year-old patient with lung adenocarcinoma and bone metastases in the lumbar vertebrae and femurs. Ossification and an increase in BMD at the metastatic sites was achieved following treatment with ZA and irradiation of the bone metastatic sites. The patient was able to maintain a normal lifestyle for over two years, despite the bone metastases. Therefore, as treatment with ZA was demonstrated to improve patient quality of life, physicians should consider this treatment strategy, particularly for the treatment of metastasis in weight-bearing bones.
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影响因子：
2.9
作者：
Nakazawa, Kensuke;Kurishima, Koichi;Hizawa, Nobuyuki
通讯作者：
Hizawa, Nobuyuki
影响因子：
6.2
作者：
Ooi, Hooi Leng;Briody, Julie;Munns, Craig F.
通讯作者：
Munns, Craig F.
影响因子：
4.4
作者：
McKeage, Kate;Plosker, Greg L.
通讯作者：
Plosker, Greg L.
影响因子：
3.3
作者：
Panigrahi, Inusha;Das, Rashmi Ranjan;Khandelwal, Niranjan
通讯作者：
Khandelwal, Niranjan
影响因子：
5.3
作者：
Chang, Chih-Chia;Chi, Kwan-Hwa;Jiang, Jiunn-Song
通讯作者：
Jiang, Jiunn-Song