Approach to the diagnosis and treatment of non-tuberculous mycobacterial disease.

Approach to the diagnosis and treatment of non-tuberculous mycobacterial disease.
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DOI:
10.1016/j.jctube.2021.100244
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发表时间:
2021-08
影响因子:
2
通讯作者:
Temesgen Z
Temesgen Z
中科院分区:
其他
文献类型:
--
作者:
Pennington KM;Vu A;Challener D;Rivera CG;Shweta FNU;Zeuli JD;Temesgen Z

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非结核分枝杆菌 (NTM) 是 190 多种分枝杆菌的统称。大多数 NTM 感染的临床表现是非特异性的,常常导致诊断延迟。使问题更加复杂的是 NTM 生物体可能很难分离。用于治疗 NTM 感染的药物可能难以让患者耐受,并且通常需要延长疗程的抗分枝杆菌治疗才能充分抑制或根除。在此,我们回顾不同的 NTM 综合征、适当的诊断测试和治疗方案。
Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190 species of Mycobacterium. The clinical presentation for most NTM infections is non-specific, often resulting in delayed diagnosis. Further complicating matters is that NTM organisms can be difficult to isolate. Medications used to treat NTM infection can be difficult for patients to tolerate, and prolonged courses of anti-mycobacterial therapy are often required for adequate suppression or eradication. Herein, we review different NTM syndromes, appropriate diagnostic tests, and treatment regimens.
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