Completion pneumonectomy for lung cancer treatment: early and long term outcomes.

Completion pneumonectomy for lung cancer treatment: early and long term outcomes.
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肺癌治疗的全肺切除术:早期和长期结果

DOI:
10.1186/1749-8090-7-107
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发表时间:
2012-10-09
影响因子:
1.6
通讯作者:
Jiang G
Jiang G
中科院分区:
医学4区
文献类型:
--
作者:
Zhang P;Jiang C;He W;Song N;Zhou X;Jiang G

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BackgroundTo分析在中国单一机构完成肺切除术治疗肺癌的经验。方法从1988年1月至2007年12月,92例患者接受了完整的肺切除术治疗肺癌。适应症为第二原发性肺癌(n = 51)、局部转移(n = 37)和肺转移(n = 4)。初次手术和CP之间的中位间隔为24.4个月(1.5-145 m)。CP手术持续4.3 h(1.5-8 h)。CP术中失血量为1854.5 ml(200-9100毫升)9(9.78%)患者在术后期间死亡:肺栓塞(n = 2),多系统衰竭后弥散性血管内凝血(DIC)(n = 1),对侧肺炎后呼吸衰竭(n = 5),支气管胸膜瘘(BPF)伴急性呼吸窘迫综合征(ARDS)1例,31例(33.7%)患者至少有1例严重非致死性并发症。结论肺癌全肺切除术虽然并发症较多,但对熟练的外科医生来说是一种安全的手术方式,远期生存率可以接受。
BackgroundTo analyze the experience of completion pneumonectomy for lung cancer at a single institution in China.MethodsFrom January 1988 to December 2007, 92 patients underwent completion pneumonectomy for the treatment of lung cancer. The indications were second primary lung cancer (n = 51), Local metastasis (n = 37) and Lung metastasis (n = 4). The median interval between the primary operation and CP was 24.4 months (1.5-145 m).ResultsThere was no intraoperative deaths. The CP procedure lasted 4.3 h (1.5-8 h). Blood loss in the CP performance was 1854.5 ml (200-9100 ml) 9 (9.78%) patients died in the postoperative period: pulmonary embolism (n = 2), disseminated intravascular coagulation (DIC) after the multisystem failure (n = 1), respiratory failure after contralateral pneumonia (n = 5), bronchopleural fistula (BPF) with acute respiratory distress syndrome (ARDS) (n = 1) 31(33.7%) patients had at least one major nonfatal complication. The 1, 3 and 5 year survival rates were 81%, 26% and 14% respectively.ConclusionsCompletion pneumonectomy for lung cancer is a safe surgical procedure for the skilled surgeon though it has a relatively higher complications and the long-term survival is acceptable.
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