Comorbidity between eating disorders and psychiatric disorders.
Comorbidity between eating disorders and psychiatric disorders.
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DOI：
10.1002/eat.23687
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发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
Petersen LV
中科院分区：
文献类型：
--
作者：
Momen NC;Plana-Ripoll O;Yilmaz Z;Thornton LM;McGrath JJ;Bulik CM;Petersen LV
先前的文献已经确定，患有其他精神疾病的个体患进食障碍的风险增加，反之亦然。然而，通常研究集中在饮食失调作为一个单一的诊断实体和/或调查选定的精神病合并症。我们进行了一项全面的研究，探索不同类型的进食障碍和所有其他精神疾病的广泛群体之间的双向关联，以确定合并症的模式。我们纳入了1963-2010年出生于丹麦的所有人。我们收集了进食障碍的信息，并使用Cox比例风险回归分析考虑了随后发生精神疾病的风险。使用竞争风险生存分析计算绝对风险。我们还考虑了先前的精神疾病和随后的饮食失调。几乎所有评估的疾病对的风险增加。在神经性厌食症（AN）诊断后，不同的后续精神疾病的中位风险比为3.80（范围2.48至6.15）;在其他进食障碍（OED）诊断后，为3.16（范围2.05至5.14）。在不同的精神疾病诊断后，晚期AN的中位风险比为2.66（范围为1.21至5.31），晚期OED的中位风险比为2.51（范围为1.25至4.10）。患有其他精神疾病的人患进食障碍的绝对风险也高于没有精神疾病的人。在这项广泛的研究中，我们发现了饮食障碍和精神障碍患者合并症风险的双向增加。虽然我们的研究结果表明，不同的模式之间的合并症进食障碍，这些变化一般很小。
Previous literature has established an increased risk of eating disorders among individuals with other psychiatric disorders and vice versa. However, often studies have focused on eating disorders as a single diagnostic entity and/or investigated selected psychiatric comorbidities. We conducted a comprehensive study, exploring bidirectional associations between different types of eating disorders and broad groups of all other psychiatric disorders, to identify patterns of comorbidity. We included all people born in Denmark 1963-2010. We collected information on eating disorders and considered the risk of subsequent psychiatric disorders using Cox-proportional hazards regression. Absolute risks were calculated using competing risks survival analyses. We also considered prior psychiatric disorders and subsequent eating disorders. An increased risk was seen for almost all disorder pairs of diagnoses evaluated. Following an anorexia nervosa (AN) diagnosis, the median hazard ratio for the different subsequent psychiatric disorders was 3.80 (range 2.48 to 6.15); following an other eating disorder (OED) diagnosis, it was 3.16 (range 2.05 to 5.14). After different psychiatric disorder diagnoses, the median hazard ratio was 2.66 for later AN (range 1.21 to 5.31) and 2.51 for later OED (range 1.25 to 4.10). Absolute risk of eating disorders were also higher among those with other psychiatric disorders than those without. In this broad examination, we identified bidirectional increases in risk of comorbidity for those with both eating disorder diagnoses and psychiatric disorder diagnoses. Although our findings indicate different patterns of comorbidity between eating disorders, these variations were generally small.
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影响因子：
8.1
作者：
McGrath, J. J.;Lim, C. C. W.;de Jonge, P.
通讯作者：
de Jonge, P.
影响因子：
25.8
作者：
Pedersen, Carsten Bocker;Mors, Ole;Eaton, William W.
通讯作者：
Eaton, William W.
影响因子：
3.4
作者：
Mors, Ole;Perto, Gurli P.;Mortensen, Preben Bo
通讯作者：
Mortensen, Preben Bo
影响因子：
--
作者：
Kessler, Ronald C.;Ormel, Johan;Petukhova, Maria;McLaughlin, Katie A.;Green, Jennifer Greif;Russo, Leo J.;Stein, Dan J.;Zaslavsky, Alan M.;Aguilar-Gaxiola, Sergio;Alonso, Jordi;Andrade, Laura;Benjet, Corina;de Girolamo, Giovanni;de Graaf, Ron;Demyttenaere, Koen;Fayyad, John;Haro, Josep Maria;Hu, Chi Yi;Karam, Aimee;Lee, Sing;Lepine, Jean-Pierre;Matchsinger, Herbert;Mihaescu-Pintia, Constanta;Posada-Villa, Jose;Sagar, Rajesh;Uestuen, T. Bedirhan
通讯作者：
Uestuen, T. Bedirhan
影响因子：
3.9
作者：
Schmidt M;Schmidt SA;Sandegaard JL;Ehrenstein V;Pedersen L;Sørensen HT
通讯作者：
Sørensen HT