Harnessing consumer smartphone and wearable sensors for clinical cancer research.

Harnessing consumer smartphone and wearable sensors for clinical cancer research.
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DOI:
10.1038/s41746-020-00351-x
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发表时间:
2020
影响因子:
15.2
通讯作者:
Low CA
Low CA
中科院分区:
医学1区
文献类型:
--
作者:
Low CA

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随着智能手机和消费者可穿戴设备变得越来越普遍,以最小的负担在真实环境中持续、被动地捕获丰富的移动传感器数据的机会越来越多。在癌症的背景下,这些被动感知的数字生物标志物的变化可能反映出功能状态、症状负担、生活质量和不良临床结果风险的有意义的变化。这些数据可以在临床会诊和更主动、更全面和更个性化的护理之间实现对患者的实时远程监控。在过去的几年里,对各种癌症人群的小型研究支持了移动传感器在肿瘤学中的可行性和潜在的临床价值。在临床肿瘤护理中实施移动传感的障碍包括管理和理解连续传感器数据的挑战、患者参与问题、难以将传感器数据集成到现有的电子健康系统和临床工作流程中,以及伦理和隐私问题。需要多学科协作来开发移动传感框架,以克服这些障碍,并可大规模实施,以远程监测癌症治疗期间或之后不断恶化的健康状况,或促进和定制生活方式或症状管理干预措施。利用数字技术有可能丰富对癌症及其治疗如何影响患者生活的科学理解,利用这种理解为患者提供更及时和个性化的支持,并改善临床肿瘤学结果。
As smartphones and consumer wearable devices become more ubiquitous, there is a growing opportunity to capture rich mobile sensor data continuously, passively, and in real-world settings with minimal burden. In the context of cancer, changes in these passively sensed digital biomarkers may reflect meaningful variation in functional status, symptom burden, quality of life, and risk for adverse clinical outcomes. These data could enable real-time remote monitoring of patients between clinical encounters and more proactive, comprehensive, and personalized care. Over the past few years, small studies across a variety of cancer populations support the feasibility and potential clinical value of mobile sensors in oncology. Barriers to implementing mobile sensing in clinical oncology care include the challenges of managing and making sense of continuous sensor data, patient engagement issues, difficulty integrating sensor data into existing electronic health systems and clinical workflows, and ethical and privacy concerns. Multidisciplinary collaboration is needed to develop mobile sensing frameworks that overcome these barriers and that can be implemented at large-scale for remote monitoring of deteriorating health during or after cancer treatment or for promotion and tailoring of lifestyle or symptom management interventions. Leveraging digital technology has the potential to enrich scientific understanding of how cancer and its treatment affect patient lives, to use this understanding to offer more timely and personalized support to patients, and to improve clinical oncology outcomes.
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