In sickness and in death: Assessing frailty in human skeletal remains.
In sickness and in death: Assessing frailty in human skeletal remains.
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疾病和死亡：评估人类骨骼遗骸的脆弱性。
DOI：
10.1002/ajpa.23019
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发表时间：
2016
影响因子：
2.8
通讯作者：
D. Crews
中科院分区：
文献类型：
--
作者：
K. Marklein;Rachael E. Leahy;D. Crews
压力在生活中的多种病态和致命后果的病因学中起着重要作用。借鉴在生活中构建的健康范式，增加了我们对压力与健康之间关系的不断发展的知识。因此，阐明压力与慢性和急性骨骼病变之间的关系可能有助于澄清我们对过去长期健康趋势的理解。在这项研究中，我们提出了一个指数的“骨骼脆弱性”，用于评估生活人群中的压力对健康的终身影响的脆弱性模型的基础上。在这里，我们评估脆弱性的考古人群的可能适用性。骨骼脆弱指数（SFI）被提议作为生物人类学家研究压力与健康之间关系的进展与生物考古学家研究压力与死者健康之间关系的方法学联系。在一个研究中世纪伦敦骨骼应力的案例研究中，SFI被应用于非僧侣（N = 60）和僧侣（N = 74）样本。我们使用方差分析/协方差分析来比较非僧侣-僧侣组、性别和年龄组之间的SFI值。结果表明，僧侣群体的终生发病率较高。这些结果补充了以前对相同伦敦人群的生物考古发现，其中观察到修道院人群的死亡风险较低，寿命较长。SFI的数据反映了在现代人群中观察到的发病率-死亡率悖论，并伴随着中世纪修道院和非修道院健康变化的生物考古学最新发现。“最终，这项研究证明了SFI在生物考古学中的实用性，通过其对常见评估的骨骼生物标志物的应用，其适用性的易用性，以及其对评估骨骼健康随时间和特定地理位置的变化的潜在有用性。
Stress plays an important role in the etiology of multiple morbid and mortal outcomes among the living. Drawing on health paradigms constructed among the living augments our evolving knowledge of relationships between stress and health. Therefore, elucidating relationships between stress and both chronic and acute skeletal lesions may help clarify our understanding of long-term health trends in the past. In this study, we propose an index of "skeletal frailty," based on models of frailty used to evaluate the life-long effects of stress on health among living populations. Here, we assess the possible applicability of frailty to archaeological populations. The skeletal frailty index (SFI) is proposed as a methodological liaison between advances made by biological anthropologists studying relationships between stress and health among the living and bioarchaeologists studying stress and health among the dead. In a case study examining skeletal stress in Medieval London, the SFI is applied to nonmonastic (N = 60) and monastic (N = 74) samples. We used analysis of variance/analysis of covariance to compare SFI values between nonmonastic-monastic groups, sexes, and age cohorts. Results indicate higher lifetime morbidity among monastic groups. These results complement previous bioarchaeological findings on the same London populations, wherein lower risks of mortality and longer lifespans were observed for monastic populations. SFI data reflect the morbidity-mortality paradox observed in modern populations and accompany recent findings in bioarchaeology of variation in Medieval monastic and nonmonastic "health." Ultimately, this study demonstrates the SFI's utility in bioarchaeology, through its application of commonly assessed skeletal biomarkers, its ease of applicability, and its potential usefulness for assessing changes in skeletal health over time and across specific geographies.
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影响因子：
5.4
作者：
Crimmins, EM;Saito, Y
通讯作者：
Saito, Y
人类恒切牙和犬齿牙釉质发育不全的时间分布。
影响因子：
3
作者：
Goodman,AH;Armelagos,GJ
通讯作者：
Armelagos,GJ
营养不良的危地马拉儿童骨骼和牙釉质形成对营养补充和发病的反应。
影响因子：
2.8
作者：
May,RL;Goodman,AH;Meindl,RS
通讯作者：
Meindl,RS
影响因子：
5.2
作者：
Anderson, A. Shane;Loeser, Richard F.
通讯作者：
Loeser, Richard F.
DOI：
10.1093/gerona/glp076
发表时间：
2009-10-01
影响因子：
5.1
作者：
Fried, Linda P.;Xue, Qian-Li;Bandeen-Roche, Karen
通讯作者：
Bandeen-Roche, Karen