Canadian surveillance study of complex regional pain syndrome in children.
Canadian surveillance study of complex regional pain syndrome in children.
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DOI：
10.1097/j.pain.0000000000002482
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发表时间：
2022-06-01
期刊：
影响因子：
7.4
通讯作者：
中科院分区：
文献类型：
--
作者：
最低儿科发病率，诊断干预措施和治疗建议的儿科医生和疼痛专家为168例儿科复杂的区域疼痛综合征的报告。本研究描述了加拿大儿科医生和疼痛诊所推荐的儿科复杂性局部疼痛综合征（CRPS）的最低发病率、临床特征和治疗方法。加拿大儿科监测项目的参与者每月报告2至18岁的CRPS新发病例，并在2017年9月至2019年8月期间完成了详细的病例报告问卷。完成描述性分析，并按性别和年龄组估计CRPS的年发病率。加拿大儿科监测项目共报告了198例病例，其中168例（84.8%）符合病例定义。加拿大CRPS的最低发病率估计为每年1.14/100，000（95%置信区间0.93-1.35/100，000）儿童。12岁及以上女孩的发病率最高（3.10，95%置信区间2.76-3.44/100，000）。CRPS诊断的平均年龄为12.2岁（SD = 2.4），从症状发作到诊断的平均时间为5.6个月（SD = 9.9），19.6%的病例无已知的激发事件。以下肢受累为主（79.8%）。非甾体类抗炎药（82.7%）和对乙酰氨基酚（66.0%）的处方率高于抗癫痫药（52.3%）和抗抑郁药（32.0%）。最常见的转诊包括物理治疗（83.3%）和多学科疼痛诊所（72.6%）;少数患者因疼痛加重而退出治疗（5.3%）。仅65.6%的病例建议进行疼痛教育。治疗差异性强调了经验数据的必要性，以支持儿科CRPS的治疗和治疗共识指南的制定。
Minimum pediatric incidence, diagnostic interventions, and treatments recommended by pediatricians and pain specialists for 168 cases of pediatric complex regional pain syndrome are reported. This study describes the minimum incidence of pediatric complex regional pain syndrome (CRPS), clinical features, and treatments recommended by pediatricians and pain clinics in Canada. Participants in the Canadian Paediatric Surveillance Program reported new cases of CRPS aged 2 to 18 years monthly and completed a detailed case reporting questionnaire from September 2017 to August 2019. Descriptive analysis was completed, and the annual incidence of CRPS by sex and age groupings was estimated. A total of 198 cases were reported to the Canadian Paediatric Surveillance Program, and 168 (84.8%) met the case definition. The minimum Canadian incidence of CRPS is estimated at 1.14/100,000 (95% confidence interval 0.93-1.35/100,000) children per year. Incidence was highest among girls 12 years and older (3.10, 95% confidence interval 2.76-3.44/100,000). The mean age of CRPS diagnosis was 12.2 years (SD = 2.4), with the mean time from symptom onset to diagnosis of 5.6 months (SD = 9.9) and no known inciting event for 19.6% of cases. Most cases had lower limb involvement (79.8%). Nonsteroidal anti-inflammatory drugs (82.7%) and acetaminophen (66.0%) were prescribed more commonly than antiepileptic drugs (52.3%) and antidepressants (32.0%). Referrals most commonly included physical therapy (83.3%) and multidisciplinary pain clinics (72.6%); a small number of patients withdrew from treatment because of pain exacerbation (5.3%). Pain education was recommended for only 65.6% of cases. Treatment variability highlights the need for empiric data to support treatment of pediatric CRPS and development of treatment consensus guidelines.
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影响因子：
7.4
作者：
Harden NR;Bruehl S;Perez RSGM;Birklein F;Marinus J;Maihofner C;Lubenow T;Buvanendran A;Mackey S;Graciosa J;Mogilevski M;Ramsden C;Chont M;Vatine JJ
通讯作者：
Vatine JJ
影响因子：
2.9
作者：
Oerlemans, HM;Oostendorp, RAB;Goris, RJA
通讯作者：
Goris, RJA
影响因子：
2.6
作者：
Lacasse, Anais;Ware, Mark A.;Choiniere, Manon
通讯作者：
Choiniere, Manon
影响因子：
5.1
作者：
Lee, BH;Scharff, L;Berde, CB
通讯作者：
Berde, CB
影响因子：
1.6
作者：
Brown, Stephen;Johnston, Bradley;McGrath, Patricia
通讯作者：
McGrath, Patricia