Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex
Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex
复制标题
人类初级体感皮层感觉输入和预测反馈的层特异性激活
DOI:
10.1126/sciadv.aav9053
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发表时间:
2019
期刊:
影响因子:
13.6
通讯作者:
Bandettini Peter A.
中科院分区:
文献类型:
--
作者:
Yu Yinghua;Huber Laurentius;Yang Jiajia;Jangraw David C.;Handwerker Daniel A.;Molfese Peter J.;Chen Gang;Ejima Yoshimichi;Wu Jinglong;Bandettini Peter A.
When humans perceive a sensation, their brains integrate inputs from sensory receptors and process them based on their expectations. The mechanisms of this predictive coding in the human somatosensory system are not fully understood. We fill a basic gap in our understanding of the predictive processing of somatosensation by examining the layer-specific activity in sensory input and predictive feedback in the human primary somatosensory cortex (S1). We acquired submillimeter functional magnetic resonance imaging data at 7T (n= 10) during a task of perceived, predictable, and unpredictable touching sequences. We demonstrate that the sensory input from thalamic projects preferentially activates the middle layer, while the superficial and deep layers in S1 are more engaged for cortico-cortical predictive feedback input. These findings are pivotal to understanding the mechanisms of tactile prediction processing in the human somatosensory cortex.
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影响因子:
9.2
作者:
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通讯作者:
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影响因子:
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作者:
MUMFORD, D
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MUMFORD, D
DOI:
10.1364/josaa.20.001434
发表时间:
2003-07-01
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