Technologies to monitor the health of loaded skin tissues.

Technologies to monitor the health of loaded skin tissues.
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DOI:
10.1186/s12938-018-0470-z
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发表时间:
2018-04-12
影响因子:
3.9
通讯作者:
Worsley PR
Worsley PR
中科院分区:
工程技术3区
文献类型:
--
作者:
Bader DL;Worsley PR

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在许多情况下,皮肤和下面的软组织受到形式为压力或压力与剪切组合的机械载荷的损害。如果持续下去,这可能会导致组织损伤,特别是邻近骨质疏松的组织,导致慢性伤口。一系列的生物工程技术已被采用,以评估加载的软组织的完整性。本文旨在回顾这些方法的量化,模拟和早期检测机械引起的皮肤损伤。该综述考虑了皮肤和支撑表面/医疗器械之间界面处的不同测量,包括压力、剪切力、摩擦力和局部微气候。的技术,以监测这些外部刺激,包括生物物理测量设备和采样的生物流体的皮肤的生理反应的潜力进行了严格的分析。此外,它还包括对医学成像技术和计算建模的分析,以提供一种可以量化组织变形和定义组织损伤阈值的方法。生物工程测量和成像技术已经提供了对负载皮肤的时间状态的洞察。尽管技术不断进步,但迄今为止,转化为稳健且具有成本效益的临床工具仍然有限。有必要调整现有的技术和模拟平台,使患者,护理人员和临床医生能够采用适当的干预策略,以尽量减少软组织损伤。
There are many situations where the skin and underlying soft tissues are compromised by mechanical loading in the form or pressure, or pressure in combination with shear. If sustained, this can lead to damage in the tissues particularly adjacent to bony prominences, resulting in chronic wounds. An array of bioengineering technologies have been adopted to assess the integrity of loaded soft tissues. This paper aims to review these approaches for the quantification, simulation and early detection of mechanically-induced skin damage. The review considers different measurements at the interface between the skin and support surface/medical device, involving pressure, shear, friction and the local microclimate. The potential of the techniques to monitor the physiological response of the skin to these external stimuli including biophysical measurement devices and sampling of biofluids are critically analysed. In addition, it includes an analysis of medical imaging technologies and computational modelling to provide a means by which tissue deformation can be quantified and thresholds for tissue damage defined. Bioengineering measurement and imaging technologies have provided an insight into the temporal status of loaded skin. Despite the advances in technology, to date, the translation to clinical tools which are robust and cost effective has been limited. There is a need to adapt existing technologies and simulation platforms to enable patients, carers and clinicians to employ appropriate intervention strategies to minimise soft tissue damage.
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