Free Energy Minimization for Vesicle Translocation Through a Narrow Pore.

Free Energy Minimization for Vesicle Translocation Through a Narrow Pore.
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通过窄孔的囊泡易位的自由能最小化。

DOI:
10.1007/978-1-0716-0806-7_13
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发表时间:
2021
影响因子:
--
通讯作者:
Murrugappan Muthukumar
Murrugappan Muthukumar
中科院分区:
--
文献类型:
--
作者:
H. Shojaei;Ahad Khaleghi Ardabili;Murrugappan Muthukumar

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本章提出了囊泡通过窄孔易位过程的数学公式。囊泡在穿过孔隙时的变形效应会导致自由能的损失,而外部驱动力的存在会起到辅助作用。我们根据弯曲和拉伸能量制定了囊泡的自由能景观,并使用 Fokker-Plank 形式来计算首次通道易位时间。我们还解决了可以对此方法进行的各种修改,以使其适用于不同的系统。
This chapter presents a mathematical formulation for the translocation process of a vesicle through a narrow pore. The effect of the deformation of the vesicle while passing through the pore causes a penalty in the free energy, while the existence of an external driving force assists. We formulate the free energy landscape of the vesicle in terms of bending and stretching energy and use Fokker-Plank formalism to calculate the first-passage translocation time. We also address various modifications that can be done to this approach to make it work for different systems.
不可压缩的囊泡通过孔隙的转移。
DOI: 10.1021/acs.jpcb.6b02079
发表时间: 2016-07-07
期刊: The journal of physical chemistry. B
影响因子: --
作者:
Shojaei HR;Muthukumar M
通讯作者: Muthukumar M