Seoul Neuropsychological Screening Battery-dementia version (SNSB-D): a useful tool for assessing and monitoring cognitive impairments in dementia patients.

Seoul Neuropsychological Screening Battery-dementia version (SNSB-D): a useful tool for assessing and monitoring cognitive impairments in dementia patients.
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DOI:
10.3346/jkms.2010.25.7.1071
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发表时间:
2010-07
影响因子:
4.5
通讯作者:
Na DL
Na DL
中科院分区:
医学4区
文献类型:
--
作者:
Ahn HJ;Chin J;Park A;Lee BH;Suh MK;Seo SW;Na DL

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首尔神经心理学筛查成套测验(SNSB)是韩国广泛使用的标准化神经心理学成套测验之一。然而,对于注意广度下降的患者来说,它可能有点太长了;并且它不提供全局认知功能(GCF)评分,这对纵向监测患者很有用。我们试图验证痴呆版本的SNSB(SNSB-D),该版本比原始SNSB短,仅包含GCF评分为300的可评分测试。我们给轻度认知障碍(MCI)(n=43)和阿尔茨海默病(AD)(n=93)患者和正常对照(NC)(n=77)服用SNSB-D。MCI和AD组的GCF评分与NC组有显著差异,并且GCF评分能够区分临床痴呆评分为0.5和1的患者。重测信度较高,AD、MCI和NC的相关系数分别为0.918、0.999和0.960。GCF评分与简易精神状态检查量表(MMSE)评分显著相关。通过ROC曲线分析,发现GCF评分比MMSE诊断更准确。SNSB-D是一种有效、可靠的整体认知功能评估工具,可用于监测痴呆患者的认知变化。
The Seoul Neuropsychological Screening Battery (SNSB) is one of the standardized neuropsychological test batteries widely used in Korea. However, it may be a bit too lengthy for patients with decreased attention span; and it does not provide the score of global cognitive function (GCF), which is useful for monitoring patients longitudinally. We sought to validate a dementia version of SNSB (SNSB-D) that was shorter than the original SNSB and contained only scorable tests with a GCF score of 300. We administered SNSB-D to patients with mild cognitive impairment (MCI) (n=43) and Alzheimer's disease (AD) (n=93), and normal controls (NC) (n=77). MCI and AD groups had GCF scores significantly different from NC group, and GCF scores were able to distinguish patients with Clinical Dementia Rating of 0.5 and 1. Test-retest reliability was high, with a correlation coefficient of 0.918 for AD, 0.999 for MCI, and 0.960 for NC. The GCF score significantly correlated with the Mini-Mental State Examination (MMSE). Through ROC-curve analysis, GCF scores were found to yield more accurate diagnoses than the MMSE. The SNSB-D is a valid, reliable tool for assessing the overall cognitive function, and can be used to monitor cognitive changes in patients with dementia.
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