Factors associated with symptom distress in women with breast cancer prior to initiation of chemotherapy.
Factors associated with symptom distress in women with breast cancer prior to initiation of chemotherapy.
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DOI：
10.1016/j.apnr.2021.151515
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发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
Rosenzweig MQ
中科院分区：
文献类型：
--
作者：
Mazanec SR;Park S;Connolly MC;Rosenzweig MQ
乳腺癌女性患者的症状困扰与早期停止化疗相关，并可能影响治疗结果。描述化疗前症状困扰的种族差异和检查症状体验的背景变量可能会让我们了解乳腺癌种族差异的复杂问题。为了确定是否感知社会支持，医疗保健系统的不信任，和经济困难预测乳腺癌妇女在首次化疗前的症状困扰。使用了一项多中心、纵向研究的描述性、相关性、横断面基线数据（N = 119），该研究比较了黑人和白色乳腺癌女性的症状经历和接受化疗的能力（R 01 MD 012245;Rosenzweig，PI）。测量工具包括症状困扰量表、人际支持评估量表、医疗保健系统不信任量表和经济困难心理感受量表。分析包括多元回归和t检验。平均而言，参与者在化疗前报告了五种症状。黑人女性报告的症状困扰高于白色女性; t（68.34）= 2.15，p = 0.035。该模型解释了26%的症状困扰方差; F（5，112）= 9.01，p <0.001。在控制年龄和种族的同时，更大的经济困难导致更高的症状困扰（β = .36，p = .001，95% CI：.34至1.34）。种族、对医疗保健系统的不信任和社会支持对症状困扰没有显著的预测作用。在开始化疗之前评估经济困难对于识别那些有更大症状困扰风险的患者至关重要。
Symptom distress in women with breast cancer is associated with early discontinuation of chemotherapy and may influence treatment outcomes. Describing racial differences in prechemotherapy symptom distress and examining contextual variables of the symptom experience may inform our understanding of the complex problem of racial disparities in breast cancer. To determine if perceived social support, healthcare system distrust, and economic hardship predict symptom distress in women with breast cancer prior to their first chemotherapy treatment. Descriptive, correlational, cross-sectional Baseline data (N = 119) was used from a multisite, longitudinal study comparing the symptom experience and ability to receive chemotherapy of Black and White women with breast cancer (R01MD012245;Rosenzweig, PI). Measures included the Symptom Distress Scale, Interpersonal Support Evaluation List, Health Care System Distrust Scale, and Psychological Sense of Economic Hardship scale. The analysis consisted of multiple regression and a t-test. On average, participants reported five symptoms prior to chemotherapy. Black women reported higher symptoms distress than White women; t(68.34) = 2.15, p = .035. The model explained 26% of variance in symptom distress; F(5, 112) = 9.01, p < .001. While controlling for age and race, greater perceived economic hardship contributed to higher symptom distress (β = .36, p = .001, 95% CI: .34 to 1.34). Race, health care system distrust and social support did not significantly predict symptom distress. Assessment of perceived financial hardship prior to beginning chemotherapy is critical to identify those patients at risk for greater symptom distress.
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DOI：
10.1002/onco.13822
发表时间：
2021-09
期刊：
The oncologist
影响因子：
--
作者：
Nielson CM;Bylsma LC;Fryzek JP;Saad HA;Crawford J
通讯作者：
Crawford J
影响因子：
4.2
作者：
Denieffe, Suzanne;Cowman, Seamus;Gooney, Martina
通讯作者：
Gooney, Martina
影响因子：
13.8
作者：
Hu X;Chehal PK;Kaplan C;Krukowski RA;Lan RH;Stepanski E;Schwartzberg L;Vidal G;Graetz I
通讯作者：
Graetz I
影响因子：
3.2
作者：
Lyon ME;Cheng YI;Needle J;Friebert S;Baker JN;Jiang J;Wang J
通讯作者：
Wang J
影响因子：
3.1
作者：
Barrera, M;Caples, H;Tein, JY
通讯作者：
Tein, JY