Non-communicable diseases among adolescents: current status, determinants, interventions and policies.
Non-communicable diseases among adolescents: current status, determinants, interventions and policies.
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DOI：
10.1186/s12889-020-09988-5
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发表时间：
2020-12-14
影响因子：
4.5
通讯作者：
Bhutta ZA
中科院分区：
文献类型：
--
作者：
Akseer N;Mehta S;Wigle J;Chera R;Brickman ZJ;Al-Gashm S;Sorichetti B;Vandermorris A;Hipgrave DB;Schwalbe N;Bhutta ZA
解决非传染性疾病（NCD）是可持续发展目标中的一个全球优先事项，特别是对青少年而言。然而，关于非传染性疾病负担、风险因素和决定因素以及针对青少年这些疾病的有效干预措施和政策的现有文献有限。这项研究开发了一个以证据为基础的概念框架，并强调了青少年（10 - 19岁）和成年期非传染性疾病发展的风险因素和干预措施之间的途径。此外，研究了青少年和预防性非传染性疾病政策/法律/立法中关键非传染性疾病风险因素和结果的流行病学概况，并进行了多变量分析，以探索青少年和成人非传染性疾病的决定因素。我们回顾了文献，以制定针对非传染性疾病的特定概念框架。从2018年1月至7月检索了全球数据存储库，以获取1990年至2016年194个国家的NCD相关风险因素、结果和政策数据。残疾调整生命年用于评估疾病负担。采用分层建模方法和普通最小二乘回归分析，探讨了非传染性疾病负担的基本和潜在原因。心理健康障碍是青少年中最常见的非传染性疾病。不良行为和生活方式因素，特别是吸烟、酗酒和吸毒、不良饮食和代谢综合征，是青春期非传染性疾病发展的关键风险因素。各国都有预防非传染性疾病相关风险因素的法律和政策，但针对避孕药具使用、减少毒品危害、心理健康和营养的法律和政策一般有限。预防非传染性疾病的有效干预措施有很多，但必须通过利用各种交付机制的多部门行动大规模实施。多变量分析表明，结构/宏观，社区和家庭因素与青少年和成人的非传染性疾病负担有显着关联。需要多部门努力，针对青少年中的非传染性疾病风险因素，以减轻成年后的疾病负担和不良后果。研究结果可以指导政策和规划，以减少可持续发展时代的非传染性疾病负担。在线版本包含补充材料，可通过10.1186/s12889 - 020 - 09988 - 5获得。
Addressing non-communicable disease (NCDs) is a global priority in the Sustainable Development Goals, especially for adolescents. However, existing literature on NCD burden, risk factors and determinants, and effective interventions and policies for targeting these diseases in adolescents, is limited. This study develops an evidence-based conceptual framework, and highlights pathways between risk factors and interventions to NCD development during adolescence (ages 10–19 years) and continuing into adulthood. Additionally, the epidemiologic profile of key NCD risk factors and outcomes among adolescents and preventative NCD policies/laws/legislations are examined, and a multivariable analysis is conducted to explore the determinants of NCDs among adolescents and adults. We reviewed literature to develop an adolescent-specific conceptual framework for NCDs. Global data repositories were searched from Jan-July 2018 for data on NCD-related risk factors, outcomes, and policy data for 194 countries from 1990 to 2016. Disability-Adjusted Life Years were used to assess disease burden. A hierarchical modeling approach and ordinary least squares regression was used to explore the basic and underlying causes of NCD burden. Mental health disorders are the most common NCDs found in adolescents. Adverse behaviours and lifestyle factors, specifically smoking, alcohol and drug use, poor diet and metabolic syndrome, are key risk factors for NCD development in adolescence. Across countries, laws and policies for preventing NCD-related risk factors exist, however those targeting contraceptive use, drug harm reduction, mental health and nutrition are generally limited. Many effective interventions for NCD prevention exist but must be implemented at scale through multisectoral action utilizing diverse delivery mechanisms. Multivariable analyses showed that structural/macro, community and household factors have significant associations with NCD burden among adolescents and adults. Multi-sectoral efforts are needed to target NCD risk factors among adolescents to mitigate disease burden and adverse outcomes in adulthood. Findings could guide policy and programming to reduce NCD burden in the sustainable development era. The online version contains supplementary material available at 10.1186/s12889-020-09988-5.
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影响因子：
168.9
作者：
Black, Robert E.;Victora, Cesar G.;Uauy, Ricardo
通讯作者：
Uauy, Ricardo
影响因子：
3.5
作者：
Botvin, Gilbert J.;Griffin, Kenneth W.;Nichols, Tracy Diaz
通讯作者：
Nichols, Tracy Diaz
DOI：
10.2471/blt.11.097253
发表时间：
2012-08-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Binagwaho, Agnes;Wagner, Claire M;Ngabo, Fidele
通讯作者：
Ngabo, Fidele
影响因子：
168.9
作者：
Baird, Sarah J.;Garfein, Richard S.;Oezler, Berk
通讯作者：
Oezler, Berk
影响因子：
168.9
作者：
Catalano, Richard F.;Fagan, Abigail A.;Shek, Daniel T. L.
通讯作者：
Shek, Daniel T. L.