A three-dimensional thalamocortical dataset for characterizing brain heterogeneity.
A three-dimensional thalamocortical dataset for characterizing brain heterogeneity.
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DOI:
10.1038/s41597-020-00692-y
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发表时间:
2020-10-20
期刊:
影响因子:
9.8
通讯作者:
Dyer EL
中科院分区:
文献类型:
--
作者:
Prasad JA;Balwani AH;Johnson EC;Miano JD;Sampathkumar V;De Andrade V;Fezzaa K;Du M;Vescovi R;Jacobsen C;Kording KP;Gürsoy D;Gray Roncal W;Kasthuri N;Dyer EL
Neural microarchitecture is heterogeneous, varying both across and within brain regions. The consistent identification of regions of interest is one of the most critical aspects in examining neurocircuitry, as these structures serve as the vital landmarks with which to map brain pathways. Access to continuous, three-dimensional volumes that span multiple brain areas not only provides richer context for identifying such landmarks, but also enables a deeper probing of the microstructures within. Here, we describe a three-dimensional X-ray microtomography imaging dataset of a well-known and validated thalamocortical sample, encompassing a range of cortical and subcortical structures from the mouse brain . In doing so, we provide the field with access to a micron-scale anatomical imaging dataset ideal for studying heterogeneity of neural structure. Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.13005527
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DOI:
10.1126/science.1260088
发表时间:
2015-01-30
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Chen F;Tillberg PW;Boyden ES
通讯作者:
Boyden ES
DOI:
10.1073/pnas.1801678115
发表时间:
2018-07-03
影响因子:
11.1
作者:
Töpperwien M;van der Meer F;Stadelmann C;Salditt T
通讯作者:
Salditt T
影响因子:
16.6
作者:
Hua Y;Laserstein P;Helmstaedter M
通讯作者:
Helmstaedter M
DOI:
10.1038/s41583-019-0250-1
发表时间:
2020-02
期刊:
Nature reviews. Neuroscience
影响因子:
--
作者:
Ueda HR;Ertürk A;Chung K;Gradinaru V;Chédotal A;Tomancak P;Keller PJ
通讯作者:
Keller PJ
影响因子:
4.6
作者:
Mizutani R;Saiga R;Ohtsuka M;Miura H;Hoshino M;Takeuchi A;Uesugi K
通讯作者:
Uesugi K