Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla.

Motion and flow insensitive adiabatic T2 -preparation module for cardiac MR imaging at 3 Tesla.
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DOI:
10.1002/mrm.24564
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发表时间:
2013-11
影响因子:
3.3
通讯作者:
Kim RJ
Kim RJ
中科院分区:
医学3区
文献类型:
--
作者:
Jenista ER;Rehwald WG;Chen EL;Kim HW;Klem I;Parker MA;Kim RJ

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用于生成T2加权的通用方法是T2准备(T2-prep)模块,该模块已成功用于1.5T下的心脏成像。虽然它已被施加在3 T,更高的磁场(B 0 ≥ 3 T)可以降低B 0和B1的均匀性,并导致不均匀的磁化制备。对于心脏成像,血流和心脏运动可能进一步损害磁化准备。在这项研究中,一种新的T2准备模块包含多个绝热B1不敏感的重聚焦(BIREF-1)脉冲的介绍和比较与三个先前描述的模块(a:复合MLEV 4,B:修改BIR-4(mBIR-4),和c:银霍尔特对)。在静态体模中,申报模块提供了与其他模块相似或更好的B 0和B1不灵敏度。在人类受试者(n=21)中,申报模块(0.10)的图像信号变异系数(CV)定量测量值(反映整体图像不均匀性)低于MLEV 4(0.15,p<0.0001)、mBIR-4(0.27,p<0.0001)和Silver-Hoult-pair(0.14,p=0.001)模块。同样,定性分析显示,所提出的模块具有最佳的图像质量分数和排名(两者,p<0.0001)。总之,我们提出了一个新的T2准备模块,这是强大的心脏成像在3 T与现有的方法相比。
A versatile method for generating T2-weighting is a T2-preparation (T2-prep) module, which has been used successfully for cardiac imaging at 1.5T. Although it has been applied at 3T, higher fields (B0 ≥ 3T) can degrade B0 and B1 homogeneity and result in non-uniform magnetization preparation. For cardiac imaging, blood flow and cardiac motion may further impair magnetization preparation. In this study, a novel T2-prep module containing multiple adiabatic B1-insensitive refocusing (BIREF-1) pulses is introduced and compared with three previously described modules (a: composite MLEV4, b: modified BIR-4 (mBIR-4), and c: Silver-Hoult–pair). In the static phantom, the proposed module provided similar or better B0 and B1 insensitivity than the other modules. In human subjects (n=21), quantitative measurement of image signal coefficient of variation (CV), reflecting overall image inhomogeneity, was lower for the proposed module (0.10) than for MLEV4 (0.15, p<0.0001), mBIR-4 (0.27, p<0.0001), and Silver-Hoult–pair (0.14, p=0.001) modules. Similarly, qualitative analysis revealed that the proposed module had the best image quality scores and ranking (both, p<0.0001). In conclusion, we present a new T2-preparation module, which is shown to be robust for cardiac imaging at 3T in comparison with existing methods.
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