Multifaceted Barriers to Rapid Roll-out of HIV Pre-exposure Prophylaxis in China: A Qualitative Study Among Men Who Have Sex with Men.

Multifaceted Barriers to Rapid Roll-out of HIV Pre-exposure Prophylaxis in China: A Qualitative Study Among Men Who Have Sex with Men.
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DOI:
10.1007/s12529-023-10177-y
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发表时间:
2024-04
影响因子:
2.7
通讯作者:
--
中科院分区:
心理学4区
文献类型:
--
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口服暴露前预防(PrEP)作为一种安全有效的基于抗逆转录病毒药物的艾滋病毒预防措施,尚未被中国同性恋、双性恋和其他男男性行为者(MSM)广泛采用。需要更深入地了解 PrEP 吸收的障碍和促进因素,以便为制定有效的干预措施提供信息。 2020 年 7 月至 8 月期间,我们对 31 名具有不同 PrEP 使用经验的中国 MSM(从未接触过 PrEP、以前和现在的 PrEP 用户)进行了一对一的半结构化访谈。采访以数字方式记录并用中文转录。根据信息-动机-行为技能模型 (IMB),我们使用主题分析方法对数据进行了分析,以确定中国 MSM 接受 PrEP 的障碍和促进因素。样本中 MSM 接受 PrEP 的主要障碍包括 PrEP 功效的不确定性和缺乏 PrEP 教育(信息)、对潜在副作用和成本的担忧(动机)以及识别真正的 PrEP 药物和管理 PrEP 护理的困难(行为技能)。促进因素包括 PrEP 在改善性生活质量和控制健康方面的明显好处。在背景层面上,我们还确定了从蓬勃发展的非正式 PrEP 市场获取 PrEP 的障碍以及与 MSM 相关的压力源。我们的研究结果表明,需要投资于 PrEP 的非歧视性公共卫生信息传递,探索在传统 HIV 护理环境之外提供有利于 MSM 的 PrEP 的选择,并在未来的 PrEP 举措中关注已建立的非正式 PrEP 市场的独特背景。 在线版本包含可在 10.1007/s12529-023-10177-y 获取的补充材料。
Oral pre-exposure prophylaxis (PrEP) as a safe and effective antiretroviral medicine-based prevention against HIV has not been widely adopted by gay, bisexual, and other men who have sex with men (MSM) in China. A deeper understanding of barriers and facilitators to PrEP uptake is needed to inform the development of effective interventions. During July–August 2020, we conducted one-on-one semi-structured interviews with 31 Chinese MSM with varied PrEP use experiences (PrEP-naïve, former, and current PrEP users). Interviews were digitally recorded and transcribed in Chinese. Informed by the Information-Motivation-Behavioral Skills Model (IMB), we analyzed the data using a thematic analysis approach to identify the barriers and facilitators to PrEP uptake among Chinese MSM. Major barriers to PrEP uptake among MSM in the sample included uncertainty about PrEP efficacy and lack of PrEP education (information), concerns over potential side effects and cost (motivation), and difficulties in identifying authentic PrEP medications and managing PrEP care (behavioral skills). Facilitators include the perceived benefit of PrEP in improving the quality of sex life and control over health. At the contextual level, we also identified barriers to PrEP access from a thriving informal PrEP market and stressors related to being MSM. Our findings identified a need to invest in non-discriminatory public health messaging of PrEP, explore options for MSM-friendly provision of PrEP outside of traditional HIV care settings, and be attentive to the unique context of an established informal PrEP market in future PrEP initiatives. The online version contains supplementary material available at 10.1007/s12529-023-10177-y.
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发表时间: 2022-05
期刊: AIDS AND BEHAVIOR
影响因子: 4.4
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Cao, Wangnan;Li, Jinghua;Sun, Shengzhi;Sturm, Carla;Peng, Liping;Gu, Jing;Hao, Chun;Hou, Fengsu;Wei, Dannuo;You, Xinyi;Deng, Yang;Ekstrom, Anna Mia
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发表时间: 2022-06
期刊: Culture, health & sexuality
影响因子: --
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DOI: 10.1007/s10461-020-03085-9
发表时间: 2021-04
期刊: AIDS and behavior
影响因子: 4.4
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通讯作者: Jonas KJ